DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kr and STP3

DIOPT Version :9

Sequence 1:	NP_001261181.1	Gene:	Kr / 38012	FlyBaseID:	FBgn0001325	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_013479.3	Gene:	STP3 / 851089	SGDID:	S000004367	Length:	343	Species:	Saccharomyces cerevisiae

Alignment Length:	392	Identity:	86/392 - (21%)
Similarity:	135/392 - (34%)	Gaps:	130/392 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SANTSATSAAAIYPAMGLQQAAAASAFGMLSPTQLLAANRQ------AAAFMAQLPMSTLANTLF 97
            :||.||.:...:.|         .|:|..|    :.||.||      :|:....||...::|
Yeast     3 NANNSAMNHITLPP---------ISSFDNL----IKAAERQYNGEASSASTHPTLPNMNISN--- 51

  Fly    98 PHNPAALFGAWAAQQSLPPQGTHLHSPPASPHSPLSTPLGSGKHPLNSPNSTPQHHEPAKKARKL 162
            ....|....:..:.|.||      ||...|..:..|:.|.|.:.|.....|..:....|..:|.:
Yeast    52 GSGSAGASSSMLSYQLLP------HSNDVSRSNSSSSFLPSVQQPTEGSASASETSSSASPSRSI 110

  Fly   163 S-VKKEFQTEISMSVNDMYHTSGGPISPPSSG-SSPNSTHDGAGGNAGCVGVSKDPSRDKSFTCK 225
            | :.|                ..||.|...:| |:|:||.           ::| |.:.|.  |.
Yeast   111 SPILK----------------VAGPSSVGGAGVSTPHSTK-----------INK-PRKKKQ--CP 145

  Fly   226 ICSRSFGYKHVLQNHERTH--TGEKPFECPECHKRFTRDHHLKTHMRLH-----TGEKPYHCSHC 283
            || |:| |.: |..|:.||  ..::|.:||.||:.|.|::.|..|.:.|     ..:.....:|.
Yeast   146 IC-RNF-YAN-LTTHKATHLTPEDRPHKCPICHRGFARNNDLLRHKKRHWKDEILSQSGVLSNHN 207

  Fly   284 D-----------------------RQFVQVANLRRHLRVHTGERPYTCEICD------------- 312
            |                       ..:.|:.:|  |....|.:.|:...:..
Yeast   208 DGKGGSVSPNDDDTHEKMTPMNSVTDYAQLKSL--HQIKGTFKCPFNSTLIQLDMDMYPYKLKPL 270

  Fly   313 ----------GKFSDSNQLKSHM-LVH----NGEK-------PFECERCHMKFRRRHHLMNHKCG 355
                      |.||..:..|:|: .:|    .|.|       |..|:.|.:||......:|...|
Yeast   271 NFETSNCHQTGVFSRCDTFKNHLKALHFEYPPGTKKKDRNVVPGRCKHCGLKFENVDVWLNEHVG 335

  Fly   356 IQ 357
            .|
Yeast   336 KQ 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kr	NP_001261181.1	C2H2 Zn finger	224..244	CDD:275368	8/19 (42%)
		zf-H2C2_2	237..261	CDD:290200	10/25 (40%)
		C2H2 Zn finger	252..272	CDD:275368	8/19 (42%)
		zf-H2C2_2	264..289	CDD:290200	5/52 (10%)
		C2H2 Zn finger	280..300	CDD:275368	5/42 (12%)
		zf-H2C2_2	292..316	CDD:290200	5/46 (11%)
		C2H2 Zn finger	308..328	CDD:275368	5/43 (12%)
		zf-H2C2_2	321..345	CDD:290200	10/35 (29%)
		C2H2 Zn finger	336..352	CDD:275368	4/15 (27%)
STP3	NP_013479.3	COG5048	<137..295	CDD:227381	35/165 (21%)
		C2H2 Zn finger	144..161	CDD:275368	8/19 (42%)
		C2H2 Zn finger	171..191	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100