DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kr and ZFP64

DIOPT Version :9

Sequence 1:NP_001261181.1 Gene:Kr / 38012 FlyBaseID:FBgn0001325 Length:502 Species:Drosophila melanogaster
Sequence 2:NP_060667.2 Gene:ZFP64 / 55734 HGNCID:15940 Length:681 Species:Homo sapiens


Alignment Length:364 Identity:95/364 - (26%)
Similarity:144/364 - (39%) Gaps:106/364 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   168 FQTEISMSVNDMYHTSGGPISPPSSGSSPNSTHDGAGGNAGCVGVSKDPSRDKSFTCKIC----- 227
            :||.:....|:  :.:...||.|:...:...|               .|...|...|  |     
Human   107 YQTYLPTESNE--NQTATVISLPAKSRTKKPT---------------TPPAQKRLNC--CYPGCQ 152

  Fly   228 -SRSFGYKHVLQNHERTHTGEKPFECPECHKRFTRDHHLKTHMRLHTGEKPYHCSHCDRQFVQVA 291
             ..::|.|. ::.|.:.|||:||.:|..|.|.|:|...||||||.|||.|||.|..||......:
Human   153 FKTAYGMKD-MERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHMRCHTGVKPYKCKTCDYAAADSS 216

  Fly   292 NLRRHLRVHTGERPYTCEI----------------------------CDGKFSDSNQLKSHMLVH 328
            :|.:|||:|:.|||:.|:|                            |..||..|:.||.||.||
Human   217 SLNKHLRIHSDERPFKCQICPYASRNSSQLTVHLRSHTGDAPFQCWLCSAKFKISSDLKRHMRVH 281

  Fly   329 NGEKPFECERCHMKFRRRHHLMNHKCGIQSPPTPALSPAMSGDYPVAISAIAIEASTNRF-AAMC 392
            :|||||:||.|:::...:.:|.:|                          |.|:.|.|.| ...|
Human   282 SGEKPFKCEFCNVRCTMKGNLKSH--------------------------IRIKHSGNNFKCPHC 320

  Fly   393 ATYGGSNESVDMEKATPEDDGPLDLSEDGASSVDGHCSNIARRKAQDIRRVFRLPPPQIPHVPSD 457
            ...|.|..::.......:.:.|...||...|     ||:.|..:..:  |:         |. :|
Human   321 DFLGDSKATLRKHSRVHQSEHPEKCSECSYS-----CSSKAALRIHE--RI---------HC-TD 368

  Fly   458 MP--------EQTEPEDLSMHSPRSIGSHEQTDDIDLYD 488
            .|        :..:|.:||.|..:..|...:|:.::..|
Human   369 RPFKCNYCSFDTKQPSNLSKHMKKFHGDMVKTEALERKD 407

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KrNP_001261181.1 C2H2 Zn finger 224..244 CDD:275368 5/25 (20%)
zf-H2C2_2 237..261 CDD:290200 10/23 (43%)
C2H2 Zn finger 252..272 CDD:275368 11/19 (58%)
zf-H2C2_2 264..289 CDD:290200 15/24 (63%)
C2H2 Zn finger 280..300 CDD:275368 7/19 (37%)
zf-H2C2_2 292..316 CDD:290200 12/51 (24%)
C2H2 Zn finger 308..328 CDD:275368 10/47 (21%)
zf-H2C2_2 321..345 CDD:290200 14/23 (61%)
C2H2 Zn finger 336..352 CDD:275368 4/15 (27%)
ZFP64NP_060667.2 COG5048 <151..450 CDD:227381 84/301 (28%)
zf-H2C2_2 161..186 CDD:290200 10/25 (40%)
C2H2 Zn finger 177..197 CDD:275368 11/19 (58%)
zf-H2C2_2 190..211 CDD:290200 15/20 (75%)
C2H2 Zn finger 205..225 CDD:275368 7/19 (37%)
zf-H2C2_2 217..239 CDD:290200 10/21 (48%)
C2H2 Zn finger 233..253 CDD:275368 2/19 (11%)
C2H2 Zn finger 261..281 CDD:275368 8/19 (42%)
zf-H2C2_2 273..297 CDD:290200 14/23 (61%)
C2H2 Zn finger 289..308 CDD:275368 6/44 (14%)
C2H2 Zn finger 373..391 CDD:275368 4/17 (24%)
zf-C2H2_6 425..450 CDD:290623
C2H2 Zn finger 427..447 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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