Protein Alignment Kr and ZNF580

DIOPT Version :10

• Sequence 1: NP_523867.1
• Gene: Kr / 38012
• FlyBaseID: FBgn0001325
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_057286.1
• Gene: ZNF580 / 51157
• HGNCID: 29473
• Length: 172
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 55/211 - (26%)
• Similarity: 76/211 - (36%)
• Gaps: 66/211 - (31%)

  Fly   114 LPPQGTHLHS---------PPASP-----HSPLSTPLGS--------GKHPLNSPNSTPQHHEPA 156
            |||:..|..|         ||.:|     ..|.|||..:        |:|.|...|..|..:
Human     4 LPPRPPHPRSSSPEAMDPPPPKAPPFPKAEGPSSTPSSAAGPRPPRLGRHLLIDANGVPYTY--- 65

  Fly   157 KKARKLSVKKEFQTEISMSVNDMYHTSGGPISPPSSGSSPNSTHDGAGGNAGCVGVSKDPSRDKS 221
                  :|:.|.:                |..||...:.|.                 :|...|.
Human    66 ------TVQLEEE----------------PRGPPQREAPPG-----------------EPGPRKG 91

  Fly   222 FTCKICSRSFGYKHVLQNHERTHTGEKPFECPECHKRFTRDHHLKTHMRLHTGE--KPYHCSHCD 284
            ::|..|:|.|.....||:|..:|:..|||.|..|.|.|.|..||..|...|...  .|:.|..|.
Human    92 YSCPECARVFASPLRLQSHRVSHSDLKPFTCGACGKAFKRSSHLSRHRATHRARAGPPHTCPLCP 156

  Fly   285 RQFVQVANLRRHLRVH 300
            |:|...|.|.:|:|:|
Human   157 RRFQDAAELAQHVRLH 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kr	NP_523867.1	SFP1	<212..324	CDD:227516	32/91 (35%)
		C2H2 Zn finger	224..244	CDD:275368	7/19 (37%)
		zf-H2C2_2	237..261	CDD:463886	11/23 (48%)
		C2H2 Zn finger	252..272	CDD:275368	8/19 (42%)
		zf-H2C2_2	264..289	CDD:463886	9/26 (35%)
		C2H2 Zn finger	280..300	CDD:275368	8/19 (42%)
		C2H2 Zn finger	308..328	CDD:275368
		zf-H2C2_2	321..345	CDD:463886
		C2H2 Zn finger	336..352	CDD:275368
ZNF580	NP_057286.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..93		25/130 (19%)
		C2H2 Zn finger	94..114	CDD:275368	7/19 (37%)
		zf-C2H2	120..142	CDD:395048	9/21 (43%)
		C2H2 Zn finger	122..142	CDD:275368	8/19 (42%)
		C2H2 Zn finger	152..172	CDD:275368	8/19 (42%)