DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kr and CG17359

DIOPT Version :9

Sequence 1:	NP_001261181.1	Gene:	Kr / 38012	FlyBaseID:	FBgn0001325	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	90/329 - (27%)
Similarity:	144/329 - (43%)	Gaps:	57/329 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DRSMSLSPPMSANTSATSAAAIYPAMGLQQ-AAAASAFGMLSPTQLLAANRQAAAFMAQLPMS-- 90
            :|.....|.::......|..:::...|:.| .....|..:.:..:|....|::..:..||.:.
  Fly    29 NRVQEQEPVLATMLRECSGCSVHKEDGMPQFICVECAEAVRNAYRLRRQCRKSHQYFEQLRLMMK 93

  Fly    91 ---------TLANTLFPHNPAALFGAWAAQQSLPPQGTHL----HSPPASPHSPLSTPL-GSGKH 141
                     .:.:.:.|..|.::..|....::..|....|    :.||..  .|:|:|| .:.:|
  Fly    94 ELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEPLLVELVQVKYMPPEP--KPISSPLPDNNEH 156

  Fly   142 PL---NSPNSTPQHHEPAKKARKLSVKKEFQTEISMSVNDMYHTSGGPISPPSSGSSPNS----T 199
            .|   .||..|| |::..::||            |.|.||.:              ||:|    .
  Fly   157 KLAQSYSPAKTP-HNKSKRRAR------------SYSDNDSW--------------SPDSELEHE 194

  Fly   200 HDGAGGNAGCVGVSKDPSR-DKSFTCKICSRSFGYKHVLQNHERTHTGEKPFECPECHKRFTRDH 263
            .|....||...|   .|.| ...:.||:|::||..|..|:.|.|.||||:|::|..|.:.|.:..
  Fly   195 DDDKIWNASKRG---KPKRVPGPYRCKLCTQSFTQKQNLEIHMRIHTGERPYKCSLCPRSFAQKG 256

  Fly   264 HLKTHMRLHTGEKPYHCSHCDRQFVQVANLRRHLRVHTGERPYTCEICDGKFSDSNQLKSHMLVH 328
            :|::|.|.||||:|:.|.:|.::|.||..|:.|.|.||||:|:.|..|...|...|.|:.||..|
  Fly   257 NLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAH 321

  Fly   329 NGEK 332
            ...|
  Fly   322 TRGK 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kr	NP_001261181.1	C2H2 Zn finger	224..244	CDD:275368	9/19 (47%)
		zf-H2C2_2	237..261	CDD:290200	11/23 (48%)
		C2H2 Zn finger	252..272	CDD:275368	6/19 (32%)
		zf-H2C2_2	264..289	CDD:290200	11/24 (46%)
		C2H2 Zn finger	280..300	CDD:275368	8/19 (42%)
		zf-H2C2_2	292..316	CDD:290200	10/23 (43%)
		C2H2 Zn finger	308..328	CDD:275368	7/19 (37%)
		zf-H2C2_2	321..345	CDD:290200	5/12 (42%)
		C2H2 Zn finger	336..352	CDD:275368
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	8/58 (14%)
		zf-C2H2	215..237	CDD:278523	9/21 (43%)
		C2H2 Zn finger	217..237	CDD:275368	9/19 (47%)
		zf-H2C2_2	229..254	CDD:290200	11/24 (46%)
		C2H2 Zn finger	245..265	CDD:275368	6/19 (32%)
		zf-H2C2_2	257..282	CDD:290200	11/24 (46%)
		C2H2 Zn finger	273..293	CDD:275368	8/19 (42%)
		zf-H2C2_2	286..310	CDD:290200	11/23 (48%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100