DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kr and bcl6aa

DIOPT Version :9

Sequence 1:NP_001261181.1 Gene:Kr / 38012 FlyBaseID:FBgn0001325 Length:502 Species:Drosophila melanogaster
Sequence 2:XP_021332488.1 Gene:bcl6aa / 393707 ZFINID:ZDB-GENE-040426-1696 Length:748 Species:Danio rerio


Alignment Length:346 Identity:109/346 - (31%)
Similarity:155/346 - (44%) Gaps:86/346 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 PMSTLANTLFPHNP--------AALFGAWAAQQSLPP--QGT----------------------- 119
            |.|.|.:...|::|        |||     ||...||  |||                       
Zfish   378 PQSPLKSDCQPNSPTESSSSKNAAL-----AQALQPPTSQGTSDPKARNWKKYKFIVLNQSSKEE 437

  Fly   120 HLHSPPASPHSPLSTPLGSGKHPLNS--PNS--TPQHHE-----PAKKARKLS---------VKK 166
            ..:.|....|||....|.:..|.::|  |:|  |.:..|     ||.:|.:|:         .::
Zfish   438 ETNPPDPGMHSPQRPGLSAFLHHVDSEHPDSKVTTKISEQGEDFPAPQASRLNNIINRSLEGSQR 502

  Fly   167 EFQTEISMSVNDMYHTSGGPISPPSSGSSPN--------------STHDGAGGNAGCVGVSKDPS 217
            ...:..|:.:|.:..:|.|..||..|...||              |.:..:....|....::..|
Zfish   503 NIDSHSSLYMNHLKCSSCGSQSPQHSDVCPNTSASRLAEEMSEMHSEYSDSSCENGTYFCNECDS 567

  Fly   218 R----------------DKSFTCKICSRSFGYKHVLQNHERTHTGEKPFECPECHKRFTRDHHLK 266
            :                ||.:.|..|..:|.||..|.:|:..||||||:.|..|..:|.|..:||
Zfish   568 KFAEEEALKRHTLQVHSDKPYKCDRCQAAFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLK 632

  Fly   267 THMRLHTGEKPYHCSHCDRQFVQVANLRRHLRVHTGERPYTCEICDGKFSDSNQLKSHMLVHNGE 331
            ||.|:|:|||||.|..|..:|||||:||.|:.:||||:||.||||..:|.....||||:.:|.||
Zfish   633 THTRIHSGEKPYKCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLRIHTGE 697

  Fly   332 KPFECERCHMKFRRRHHLMNH 352
            ||:.||:|::.||.:..|..|
Zfish   698 KPYHCEKCNLHFRHKSQLRLH 718

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KrNP_001261181.1 C2H2 Zn finger 224..244 CDD:275368 7/19 (37%)
zf-H2C2_2 237..261 CDD:290200 11/23 (48%)
C2H2 Zn finger 252..272 CDD:275368 9/19 (47%)
zf-H2C2_2 264..289 CDD:290200 14/24 (58%)
C2H2 Zn finger 280..300 CDD:275368 10/19 (53%)
zf-H2C2_2 292..316 CDD:290200 13/23 (57%)
C2H2 Zn finger 308..328 CDD:275368 9/19 (47%)
zf-H2C2_2 321..345 CDD:290200 13/23 (57%)
C2H2 Zn finger 336..352 CDD:275368 6/15 (40%)
bcl6aaXP_021332488.1 BTB 66..172 CDD:306997
DMP1 <284..558 CDD:311295 40/184 (22%)
C2H2 Zn finger 562..583 CDD:275368 1/20 (5%)
C2H2 Zn finger 590..610 CDD:275368 7/19 (37%)
zf-H2C2_2 602..627 CDD:316026 11/24 (46%)
C2H2 Zn finger 618..638 CDD:275368 9/19 (47%)
zf-H2C2_2 630..655 CDD:316026 14/24 (58%)
C2H2 Zn finger 646..666 CDD:275368 10/19 (53%)
zf-H2C2_2 658..683 CDD:316026 14/24 (58%)
C2H2 Zn finger 674..694 CDD:275368 9/19 (47%)
zf-H2C2_2 687..711 CDD:316026 13/23 (57%)
C2H2 Zn finger 702..720 CDD:275368 7/17 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E33208_3BISR
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 141 1.000 Inparanoid score I4462
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4623
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.890

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