DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kr and sug

DIOPT Version :9

Sequence 1:NP_001261181.1 Gene:Kr / 38012 FlyBaseID:FBgn0001325 Length:502 Species:Drosophila melanogaster
Sequence 2:NP_610826.1 Gene:sug / 36424 FlyBaseID:FBgn0033782 Length:384 Species:Drosophila melanogaster


Alignment Length:449 Identity:96/449 - (21%)
Similarity:155/449 - (34%) Gaps:151/449 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   111 QQSLPPQGTH---LHSPPASPHSPLSTP--------LGS--GKHPLNSPNSTPQHHE-------- 154
            |:|:...|.|   ::.||....:|.:||        .||  ..|..:......||.:        
  Fly     5 QKSIFNSGPHSRGIYEPPLGYFTPYNTPPYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQHIRFP 69

  Fly   155 -----PAKKARKLSVKKEFQTEISMSVNDMYHTSGGPIS-PPSSGSSPNSTHDGAGGNAGCVGVS 213
                 |.:.......::..|:.|..:..........|:. |..|.|..:|:..|...:..|....
  Fly    70 TPPITPPRPIAGYGYRQRTQSVIMKARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCNWTD 134

  Fly   214 KDPSRD---------------KSFT----------CKICSRSFGYKHVLQNHERTHTGEKPFECP 253
            .|...|               .|.|          |:...|.|..::.:..|.||||.|||..|.
  Fly   135 CDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCH 199

  Fly   254 ECHKRFTRDHHLKTHMRLHTGEKPYHCSH--CDRQFVQVANLRRHLRVHTGERPYTCEI--CDGK 314
            .|.|.|:|..:||.|:|.|:|||||.||.  |.:.:...::..:|.|.|:.|:||.|::  |..:
  Fly   200 LCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKR 264

  Fly   315 FSDSNQLKSHMLVHNGEKPFECERCHMKFRRRHHLMNHKCGIQSPPTPALSPAMSGDYPVAISAI 379
            ::|.:.|:.|:               ..|:...||:..: .:..|..|.|               
  Fly   265 YTDPSSLRKHV---------------KTFKHSIHLIASQ-PLTLPSVPCL--------------- 298

  Fly   380 AIEAST-NRFAAMCATYGGSNESVDMEKATPEDDGPLDLSEDGASSVDGHCSNIARRKAQDIRRV 443
             :|||: :.|..:.|                            ||||:...|:.:.|...|    
  Fly   299 -LEASSESAFTCLPA----------------------------ASSVESTSSSSSARYYDD---- 330

  Fly   444 FRLPPPQIPHVPSDMPEQTEPEDLSMHSPRSIGSHEQTDDIDLYDLDDAPASYMGHQQH 502
                            ...||.|.|: .|:.             |.:.:|:.::|.:||
  Fly   331 ----------------SNNEPSDYSL-KPKQ-------------DAEFSPSYWLGDRQH 359

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KrNP_001261181.1 C2H2 Zn finger 224..244 CDD:275368 5/19 (26%)
zf-H2C2_2 237..261 CDD:290200 12/23 (52%)
C2H2 Zn finger 252..272 CDD:275368 9/19 (47%)
zf-H2C2_2 264..289 CDD:290200 13/26 (50%)
C2H2 Zn finger 280..300 CDD:275368 5/21 (24%)
zf-H2C2_2 292..316 CDD:290200 8/25 (32%)
C2H2 Zn finger 308..328 CDD:275368 5/21 (24%)
zf-H2C2_2 321..345 CDD:290200 3/23 (13%)
C2H2 Zn finger 336..352 CDD:275368 3/15 (20%)
sugNP_610826.1 C2H2 Zn finger 170..190 CDD:275368 5/19 (26%)
zf-H2C2_2 183..207 CDD:290200 12/23 (52%)
COG5048 192..>271 CDD:227381 30/78 (38%)
C2H2 Zn finger 198..218 CDD:275368 9/19 (47%)
zf-H2C2_2 210..237 CDD:290200 13/26 (50%)
C2H2 Zn finger 226..248 CDD:275368 5/21 (24%)
C2H2 Zn finger 256..277 CDD:275368 5/35 (14%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 54 1.000 Inparanoid score I1809
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.960

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