Protein Alignment Kr and ZNF865

DIOPT Version :10

• Sequence 1: NP_523867.1
• Gene: Kr / 38012
• FlyBaseID: FBgn0001325
• Length: 502
• Species: Drosophila melanogaster
• Sequence 2: NP_001182534.1
• Gene: ZNF865 / 100507290
• HGNCID: 38705
• Length: 1059
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 133/556 - (23%)
• Similarity: 186/556 - (33%)
• Gaps: 209/556 - (37%)

  Fly    17 ALAGIKQEDVHLDRSMSLSPPMSANTSATSAA-----------AIYPAMGLQQAAAASAFGMLSP 70
            |..|..|...||.   .|..|..|.::||:||           .:.||.....:||.:..|:..|
Human   280 AAGGPPQPGPHLP---PLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPP 341

  Fly    71 T--------------------------QLL--------------AANRQA---------AAFMAQ 86
            .                          |::              :.||:.         :|.:.:
Human   342 ATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLR 406

  Fly    87 LPMSTL------ANTLFPHN---------------PAALFG-AWAAQQSLPPQGTHLHSPPA--- 126
            ||....      |:.|..|.               |..|.| :::|.||| .:....|:|||
Human   407 LPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSL-LRHKAAHAPPAAAA 470

  Fly   127 ---------SPHSPLSTPLGSGKHPLNSPNSTPQHHEPAKKARKLSVKKEFQTEISMSVNDMYHT 182
                     :|..|.:.|.|....|.:.|.:..:....|..|                  .:|
Human   471 EAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAA------------------VVY-- 515

  Fly   183 SGGPISPPSSGSSP----NSTHDGAGGNAGCVGVSKDPSRDKSFTCKICSRSFGYKHVLQNHERT 243
              |.:..|..|:.|    .:...||||:...|     |.  |:|.|.||.|.||.:..|:.|||.
Human   516 --GAVPVPLLGAHPLLLGGAGTSGAGGSGASV-----PG--KTFCCGICGRGFGRRETLKRHERI 571

  Fly   244 HTGEKPFECPECHKRFTRDHHLKTHMRLHTGEKPYHCSHCDRQFVQVANLRRHLRVHTGERP--- 305
            ||||||.:||.|.|||....||..|..:||.|:||.|..|.:.|....:|.||.:||..:.|
Human   572 HTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCAL 636

  Fly   306 --------------------------------YTCEICDGKFSDSNQLKSHMLVHNGEKPFECER 338
                                            |.|..|...|.|...:.||..||..|||:.|:.
Human   637 AGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDA 701

  Fly   339 CHMKFRRRHHLMNHKCGIQSPPTPALSPA----------------------MSGDYPVAISAIA- 380
            |...|....:||.||...|:.|...|.||                      ::|:...|::|:|
Human   702 CGKTFGFIENLMWHKLVHQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAALAG 766

  Fly   381 ------------------IEASTNRFAAMCATYGGS 398
                              ..:...||:  |||.|.|
Human   767 VSGGEDAGGAAVAGAGGGASSGPERFS--CATCGQS 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kr	NP_523867.1	SFP1	<212..324	CDD:227516	47/146 (32%)
		C2H2 Zn finger	224..244	CDD:275368	10/19 (53%)
		zf-H2C2_2	237..261	CDD:463886	16/23 (70%)
		C2H2 Zn finger	252..272	CDD:275368	9/19 (47%)
		zf-H2C2_2	264..289	CDD:463886	11/24 (46%)
		C2H2 Zn finger	280..300	CDD:275368	6/19 (32%)
		C2H2 Zn finger	308..328	CDD:275368	6/19 (32%)
		zf-H2C2_2	321..345	CDD:463886	10/23 (43%)
		C2H2 Zn finger	336..352	CDD:275368	5/15 (33%)
ZNF865	NP_001182534.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	58..142
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..206
		C2H2 Zn finger	226..246	CDD:275368
		C2H2 Zn finger	254..274	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	275..342		17/64 (27%)
		COG5048	349..>421	CDD:227381	7/71 (10%)
		C2H2 Zn finger	352..372	CDD:275368	1/19 (5%)
		C2H2 Zn finger	380..400	CDD:275368	2/19 (11%)
		C2H2 Zn finger	409..426	CDD:275368	2/16 (13%)
		C2H2 Zn finger	443..460	CDD:275370	6/17 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	461..503		10/41 (24%)
		C2H2 Zn finger	552..572	CDD:275368	10/19 (53%)
		zf-H2C2_2	565..587	CDD:463886	14/21 (67%)
		C2H2 Zn finger	580..600	CDD:275368	9/19 (47%)
		C2H2 Zn finger	608..628	CDD:275368	6/19 (32%)
		C2H2 Zn finger	671..691	CDD:275368	6/19 (32%)
		C2H2 Zn finger	699..719	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	726..747		3/20 (15%)
		C2H2 Zn finger	794..814	CDD:275368	5/7 (71%)
		C2H2 Zn finger	822..842	CDD:275368
		C2H2 Zn finger	850..870	CDD:275368
		C2H2 Zn finger	878..898	CDD:275368
		C2H2 Zn finger	906..926	CDD:275368
		C2H2 Zn finger	934..954	CDD:275368
		C2H2 Zn finger	962..982	CDD:275368
		C2H2 Zn finger	991..1011	CDD:275368
		C2H2 Zn finger	1019..1039	CDD:275368