DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment lov and Zbtb37

DIOPT Version :10

Sequence 1:NP_611994.3 Gene:lov / 38007 FlyBaseID:FBgn0266129 Length:1143 Species:Drosophila melanogaster
Sequence 2:NP_001100661.1 Gene:Zbtb37 / 304918 RGDID:1308731 Length:504 Species:Rattus norvegicus


Alignment Length:673 Identity:120/673 - (17%)
Similarity:203/673 - (30%) Gaps:257/673 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 NHILRAFDALLKTKTLVDVTLVCAETSIRAHKMVLSACSPFFQ--------RVFAETPCKHPVIV 180
            |.:|...:.|.....|.|:.:.....:.||||:||:|.||:|:        ...:.:..|:|.  
  Rat    18 NSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPT-- 80

  Fly   181 LKDFRGWVVQAIVDFMYRGEISVPQQRLQTLIQAGESLQVRGLVES------------SVPE--- 230
                   |.:.::.|.|.|.|.:....:.:.:.|...||::.:::.            :|.|   
  Rat    81 -------VFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEA 138

  Fly   231 -----HTPTPAASPDDFGMLDTSMLSSTFEDECPTMVR-------PSKGGKLLMPSARLFGNASS 283
                 .|..|...|:...:             .|.:.|       .|||        ...|..|:
  Rat   139 ELSQTRTKHPERPPESHRV-------------TPNLTRSLSPRHNASKG--------NWRGQVSA 182

  Fly   284 AIAALGLRRKREQESDRDLESDQELGGSSPMPRRKQARPRRRSGDVPHDFTLNKTDAESLQTVIK 348
            .:....|....|..|.:.:|...::.|..|:.|                  :|:.....::|.| 
  Rat   183 VLDIRELSPPEESTSPQIIEQSSDVEGREPILR------------------INRAGQWYVETGI- 228

  Fly   349 HELLERAERDQEEAPDQDNSQGEAEKISSSPAKTLVERAKEQKSMKEEGSDQPRSLNENHHQLEL 413
                          .||....|                            |:.|.|...|.:.| 
  Rat   229 --------------ADQGPQSG----------------------------DEVRVLGAVHIKTE- 250

  Fly   414 DDEDDDDQDHEEEEEQDIEELIHTTNELRRQAAAAAANAAAMSPNPSPCLSDGPEDLCTTKKGKE 478
                            ::||.:...|:...:..::|...|||..:.:...|.|.|.......|.:
  Rat   251 ----------------NLEEWLGPENQPSGEDGSSAEEVAAMVIDTTGHGSVGQESYTLGSSGAK 299

  Fly   479 LISGPSSSADCESNNNNSSKLQDNNQRIMLSLKDIRQLNANPNPTAIHTPTSCSGGNNGLLTFPP 543
            :....||..|..|.:.:           ::|:            |..|...|.|           
  Rat   300 VARPTSSEVDRFSPSGS-----------VVSM------------TERHRARSES----------- 330

  Fly   544 PGLRPPGLPDSPPCHMEALEAQMHAAAAAAVAAAGSGEHPFHHMEH--QMEMS---------LAA 597
                 ||..|.|    :.|.:|:..:|...|:|         ::|:  :.|:|         |..
  Rat   331 -----PGRMDEP----KQLSSQVEESAMMGVSA---------YVEYLREQEVSERWFRYNPRLTC 377

  Fly   598 AAAAAAMHQREPRDPRDGRDHNAFASNLLGPMGMPPFGGHNGGHPGNSGPGNGCPGQAAHERLEE 662
            ...|.:.:|:...| |..|.|          ||:.||.....|              ..:.|.::
  Rat   378 IYCAKSFNQKGSLD-RHMRLH----------MGITPFVCRMCG--------------KKYTRKDQ 417

  Fly   663 SMNRLSKELG-KEF-----GKEF------GKEFGKEFGPASPMSLQGPFN-----------APDG 704
            ....:.|..| |.|     ||.|      .:.|.|......|  |:||.:           |.:|
  Rat   418 LEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIP--LEGPHSISPETTVTSRQAEEG 480

  Fly   705 -PPHPPSPLPFPGMSSAMTLTPP 726
             |.|..:..|......:::.|.|
  Rat   481 SPSHEETVAPGESAQGSVSTTGP 503

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lovNP_611994.3 BTB_POZ_BAB-like 139..222 CDD:349624 22/90 (24%)
HTH_psq 791..834 CDD:283007
Zbtb37NP_001100661.1 BTB_POZ_ZBTB37 9..131 CDD:349531 25/121 (21%)
C2H2 Zn finger 377..397 CDD:275368 5/20 (25%)
zf-H2C2_2 389..414 CDD:463886 9/49 (18%)
zf-C2H2 403..425 CDD:395048 3/35 (9%)
C2H2 Zn finger 405..425 CDD:275368 2/33 (6%)
zf-H2C2_2 418..440 CDD:463886 6/21 (29%)
C2H2 Zn finger 433..451 CDD:275368 3/17 (18%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.