DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gol and HRD1

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_014630.1	Gene:	HRD1 / 854149	SGDID:	S000005373	Length:	551	Species:	Saccharomyces cerevisiae

Alignment Length:	284	Identity:	52/284 - (18%)
Similarity:	102/284 - (35%)	Gaps:	85/284 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 IEGR----RGVRTISSLNRTSV---LFVSISFIVLMIISLVWLIFYYIQR----FRYMQAKDQQS 271
            :||:    :.:...:...:|::   :.:.....::::..:||.|....|.    ::..:...|..
Yeast   264 LEGKFMYEKAIDVFTRFLKTALHLSMLIPFRMPMMLLKDVVWDILALYQSGTSLWKIWRNNKQLD 328

  Fly   272 RNLCSVTKKAIMKIPTKTGKFSDEKDLDSDCCAICIEAY--------------KPTDTIRILPCK 322
            ..|.:||.:.:.....           |.:.|.||::..              ||    :.|||.
Yeast   329 DTLVTVTVEQLQNSAN-----------DDNICIICMDELIHSPNQQTWKNKNKKP----KRLPCG 378

  Fly   323 HEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYV----FLGSEESILEYQPDPPQGLA--------- 374
            |..|.:|:..|:...:|||:|:|.|....|.|    |..:.:...:.......|:|
Yeast   379 HILHLSCLKNWMERSQTCPICRLPVFDEKGNVVQTTFTSNSDITTQTTVTDSTGIATDQQGFANE 443

  Fly   375 --LVEARDESADLN------------RSRDFVVDFPRVFVLDSGCVVGAREMLFPCRIPERSQSS 425
              |:..|..|.|:.            |:|......|..:.             ||  :.:...:|
Yeast   444 VDLLPTRTTSPDIRIVPTQNIDTLAMRTRSTSTPSPTWYT-------------FP--LHKTGDNS 493

  Fly   426 L-SLRQARDWVSLMSNKLEEQQGL 448
            : |.|.|.::  |::|..|::.|:
Yeast   494 VGSSRSAYEF--LITNSDEKENGI 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037
		UPF0233	226..>258	CDD:299753	4/34 (12%)
		zf-RING_2	301..344	CDD:290367	15/56 (27%)
HRD1	NP_014630.1	HRD1	5..551	CDD:227568	52/284 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910