DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gol and APE3

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_009845.2	Gene:	APE3 / 852589	SGDID:	S000000490	Length:	537	Species:	Saccharomyces cerevisiae

Alignment Length:	172	Identity:	39/172 - (22%)
Similarity:	69/172 - (40%)	Gaps:	66/172 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 MEDRIAVDVYN------YAFLNWSYVEHGN--MLCNMEFAQEQARYGEGKVLNV----------- 103
            ::|:|.||..|      |...|:|..::|:  .:...:...:...|    :|||
Yeast    75 LQDKIKVDDLNATAWDLYRLANYSTPDYGHPTRVIGSKGHNKTMEY----ILNVFDDMQDYYDVS 135

  Fly   104 -------TGRLIHITATD-----NFSDD--YACTPYIRGTLG--APIPDKG-------------- 138
                   :|::|....:|     :|::.  :|.:|.:.|.:|  ..||:.|
Yeast   136 LQEFEALSGKIISFNLSDAETGKSFANTTAFALSPPVDGFVGKLVEIPNLGCEEKDYASVVPPRH 200

  Fly   139 -ETWIALVRRGRCTFEEKVKHVYQQNAAG------VIIYNDK 173
             |..|||:.||:|.|.:|      .|.||      |:||:::
Yeast   201 NEKQIALIERGKCPFGDK------SNLAGKFGFTAVVIYDNE 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	33/151 (22%)
		UPF0233	226..>258	CDD:299753
		zf-RING_2	301..344	CDD:290367
APE3	NP_009845.2	M28_SGAP_like	78..506	CDD:349873	38/169 (22%)
APE3	NP_009845.2	PA_ScAPY_like	155..284	CDD:239045	23/88 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910