DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and TTC3

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_016883947.1	Gene:	TTC3 / 7267	HGNCID:	12393	Length:	2081	Species:	Homo sapiens

Alignment Length:	135	Identity:	33/135 - (24%)
Similarity:	59/135 - (43%)	Gaps:	18/135 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 VRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVT--------KK 280
            ::.:.|.|:.|:..:||..||..:..   .|....::.:....||:::....|.|        ..
Human  1923 IKKVRSKNKNSLSGLSIDEIVQRVTE---HILDEQKKKKPNPGKDKRTYEPSSATPVTRSSQGSP 1984

  Fly   281 AIMKIPTKTGKFSDEKD------LDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRT 339
            :::..|:...|....:|      |.:..|.||.|.:| :..:|:|.|.|::||.|...||.....
Human  1985 SVVVAPSPKTKGQKAEDVPVRIALGASSCEICHEVFK-SKNVRVLKCGHKYHKGCFKQWLKGQSA 2048

  Fly   340 CPMCK 344
            ||.|:
Human  2049 CPACQ 2053

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037
		UPF0233	226..>258	CDD:299753	8/31 (26%)
		zf-RING_2	301..344	CDD:290367	16/42 (38%)
TTC3	XP_016883947.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910