DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and Rnf133

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001037743.1	Gene:	Rnf133 / 681395	RGDID:	1596695	Length:	381	Species:	Rattus norvegicus

Alignment Length:	291	Identity:	94/291 - (32%)
Similarity:	145/291 - (49%)	Gaps:	33/291 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 AFLNWSYVEHGNMLCNMEFAQEQARYGEGKVLNVTGRLIHITATDNFSDDYACTP---YIRGTLG 131
            |::|.|:.....||..:   .|...:|...:|.   |:..:..........||.|   :|
  Rat    40 AYMNISFHVGNRMLSEL---GETGVFGRSSILK---RVAGVVVPPEGKIQNACDPNTSFI----- 93

  Fly   132 APIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYN----DKQVMQLEKMQIKGKTRNIAA 192
              :|...|.||||:.||.|.|.:|:|...:..|.||||||    ..||..:.....:    :|..
  Rat    94 --LPRNKEPWIALIERGGCAFTQKIKVASENGARGVIIYNFPGTGNQVFPMSHQAFE----DIVV 152

  Fly   193 VITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYY 257
            |:.....|.::...:.||.:||:.:..||:.|..::        ...:||:::...:|.:..||:
  Rat   153 VMIGNVKGMEILHLIRKGVHVTVMVEVGRKHVIWLN--------HYFVSFMIVTTATLAYFTFYH 209

  Fly   258 IQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSDEK-DLDSDCCAICIEAYKPTDTIRILPC 321
            |:|....:.:|::.:.|....|||..::..:..|..||: ..::|.|.||.|||||.:.:|||.|
  Rat   210 IRRLWVARIEDRRWKRLTRELKKAFGQLQVRILKEGDEEVSPNADSCVICFEAYKPNEIVRILTC 274

  Fly   322 KHEFHKNCIDPWLIEHRTCPMCKLDVLKFYG 352
            ||.|||||||||::.|.||||||.|:||..|
  Rat   275 KHFFHKNCIDPWILAHGTCPMCKCDILKALG 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	40/150 (27%)
		UPF0233	226..>258	CDD:299753	5/31 (16%)
		zf-RING_2	301..344	CDD:290367	29/42 (69%)
Rnf133	NP_001037743.1	PA_GRAIL_like	43..177	CDD:239037	40/150 (27%)
		HRD1	<183..>368	CDD:227568	51/131 (39%)
		RING-H2_RNF128_like	254..302	CDD:319716	32/47 (68%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	340..381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020