Protein Alignment gol and Rnf133

DIOPT Version :10

• Sequence 1: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001037743.1
• Gene: Rnf133 / 681395
• RGDID: 1596695
• Length: 381
• Species: Rattus norvegicus
• Alignment Length: 291
• Identity: 94/291 - (32%)
• Similarity: 145/291 - (49%)
• Gaps: 33/291 - (11%)

  Fly    70 AFLNWSYVEHGNMLCNMEFAQEQARYGEGKVLNVTGRLIHITATDNFSDDYACTP---YIRGTLG 131
            |::|.|:.....||..:   .|...:|...:|.   |:..:..........||.|   :|
  Rat    40 AYMNISFHVGNRMLSEL---GETGVFGRSSILK---RVAGVVVPPEGKIQNACDPNTSFI----- 93

  Fly   132 APIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYN----DKQVMQLEKMQIKGKTRNIAA 192
              :|...|.||||:.||.|.|.:|:|...:..|.||||||    ..||..:.....:    :|..
  Rat    94 --LPRNKEPWIALIERGGCAFTQKIKVASENGARGVIIYNFPGTGNQVFPMSHQAFE----DIVV 152

  Fly   193 VITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYY 257
            |:.....|.::...:.||.:||:.:..||:.|..::        ...:||:::...:|.:..||:
  Rat   153 VMIGNVKGMEILHLIRKGVHVTVMVEVGRKHVIWLN--------HYFVSFMIVTTATLAYFTFYH 209

  Fly   258 IQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSDEK-DLDSDCCAICIEAYKPTDTIRILPC 321
            |:|....:.:|::.:.|....|||..::..:..|..||: ..::|.|.||.|||||.:.:|||.|
  Rat   210 IRRLWVARIEDRRWKRLTRELKKAFGQLQVRILKEGDEEVSPNADSCVICFEAYKPNEIVRILTC 274

  Fly   322 KHEFHKNCIDPWLIEHRTCPMCKLDVLKFYG 352
            ||.|||||||||::.|.||||||.|:||..|
  Rat   275 KHFFHKNCIDPWILAHGTCPMCKCDILKALG 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	40/150 (27%)
		HRD1	<237..>347	CDD:227568	46/110 (42%)
		RING-H2_RNF130-like	302..347	CDD:438330	30/44 (68%)
Rnf133	NP_001037743.1	PA_GRAIL_like	43..177	CDD:239037	40/150 (27%)
		HRD1	<183..>368	CDD:227568	51/131 (39%)
		RING-H2_RNF128-like	254..302	CDD:438454	32/47 (68%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	340..381