Protein Alignment gol and RNF150

DIOPT Version :9

• Sequence 1: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_005263207.1
• Gene: RNF150 / 57484
• HGNCID: 23138
• Length: 460
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 122/318 - (38%)
• Similarity: 178/318 - (55%)
• Gaps: 45/318 - (14%)

  Fly    70 AFLNWSYVE-----------HGNMLCNMEFAQEQARYGE-GKVLNVTGRLIHITATDNFSDDYAC 122
            ||:|.:|.|           .|....:.| ..|..|||| ....:..|.::..::.   .|..||
Human    42 AFVNITYAEPAPDPGAGAAGGGGAELHTE-KTECGRYGEHSPKQDARGEVVMASSA---HDRLAC 102

  Fly   123 TPYIRGTLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYN---------------- 171
            .|..:    ...|.:|:.||||:.:|.||:.:|:::.:.|||:.|:|:|
Human   103 DPNTK----FAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPHAGL 163

  Fly   172 ---DKQVMQLEK---MQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSL 230
               ..|.::|..   ..:.....:|.|::..:..|:::...|::...||:.|..|.|.::  ..:
Human   164 MSSHAQPLKLISPCPYSLSSGVEDIVAIMIPEPKGKEIVSLLERNITVTMYITIGTRNLQ--KYV 226

  Fly   231 NRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSD- 294
            :||||:||||||||||||||.||:|||||||||..|:|:..|.|....||||.|:..:|.|..|
Human   227 SRTSVVFVSISFIVLMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQIRTIKKGDK 291

  Fly   295 EKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYG 352
            |.:.|.|.||:|||.|||.|.:|||||:|.|||:|:||||::||||||||:::||..|
Human   292 ETESDFDNCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALG 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	39/177 (22%)
		UPF0233	226..>258	CDD:299753	22/31 (71%)
		zf-RING_2	301..344	CDD:290367	30/42 (71%)
RNF150	XP_005263207.1	PA_GRAIL_like	45..215	CDD:239037	39/177 (22%)
		UPF0233	<229..>254	CDD:299753	21/24 (88%)
		zf-RING_2	298..341	CDD:290367	30/42 (71%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145920
Domainoid	1	1.000	90	1.000	Domainoid score	I7788
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3586
Isobase	1	0.950	-	0	Normalized mean entropy	S3321
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		otm41809
orthoMCL	1	0.900	-	-		OOG6_107948
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3602
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.840