DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and znrf3

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001295484.1	Gene:	znrf3 / 556813	ZFINID:	ZDB-GENE-070705-263	Length:	866	Species:	Danio rerio

Alignment Length:	287	Identity:	68/287 - (23%)
Similarity:	124/287 - (43%)	Gaps:	80/287 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 DYACTPYIRG------TLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYNDKQVMQ 177
            ||  |.|..|      ..||.|..:||. :.:...|.|...:: :.:|:....||:        :
Zfish    47 DY--TTYTTGLQGRFSRAGATISAEGEI-VQMHPLGLCNNNDE-EDLYEYGWVGVV--------K 99

  Fly   178 LEK-------MQIKGKT-----RNIAAVITYQNIGQDLSLTLDKGYNVT-------ISIIEGRRG 223
            ||:       :.:.||.     |...|||...:...|   .:|:...|:       :..::|...
Zfish   100 LEQPELDPSCLTVLGKAKRAVQRGATAVIFDVSENPD---AIDQLNQVSEDPLKRPVVYVKGTDA 161

  Fly   224 VRTISSLNRTSV-------------------LFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQ 269
            |:.::.:|:..|                   :|::. |:|:.::.|:.||     :.:..|.:.|
Zfish   162 VKLMNIVNKQKVARARIQHRPPRPTEYFDMGIFLAF-FVVVSLVCLILLI-----KIKLKQRRSQ 220

  Fly   270 QSRNLCSVTKKAIMKIPTKTGKFSDEKDLDSDC-------------CAICIEAYKPTDTIRILPC 321
            .|.|..::  :|:.|:.|...|...:...::.|             ||||:|.|...:.:|::||
Zfish   221 SSMNRMAI--QALEKMETCKFKAKFKGQREASCGASDSVSSSSTSDCAICLEKYIDGEELRVIPC 283

  Fly   322 KHEFHKNCIDPWLIEHRTCPMCKLDVL 348
            .|.|||.|:||||::|.|||.|:.:::
Zfish   284 AHRFHKKCVDPWLLQHHTCPHCRHNII 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	26/122 (21%)
		UPF0233	226..>258	CDD:299753	8/50 (16%)
		zf-RING_2	301..344	CDD:290367	23/55 (42%)
znrf3	NP_001295484.1	zf-RING_2	265..306	CDD:290367	22/40 (55%)
znrf3	NP_001295484.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920