DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and rnf130

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_009289393.1	Gene:	rnf130 / 553950	ZFINID:	ZDB-GENE-050522-525	Length:	428	Species:	Danio rerio

Alignment Length:	339	Identity:	132/339 - (38%)
Similarity:	192/339 - (56%)	Gaps:	23/339 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LPPLTFPATTTTLVAAMSIANQDLERYFRPGNGTHSFSGMEDRIAVDVYNY--AFLNWSYVEH-G 80
            |..|..||:.::.:.|:.:|      :..|   ..|.|...|:..|:..:|  |.:|.:.::| |
Zfish     2 LKRLAAPASCSSCLLALLLA------FVSP---RCSLSIGADKTMVNKEDYYSAIVNATVLDHKG 57

  Fly    81 NMLCNMEFAQEQARYGEGK-VLNVTGRLIHITATDNFSDDYACTPYIRGTLGAPIPDKGETWIAL 144
            |.  .....:...|||:.. .....|.::...|.:...|...|.|:.|..    :|.|...|:|:
Zfish    58 NP--QQMVTKNDGRYGQNSPKTEAKGIVVAPAAVNGAVDLQGCCPHTRFI----VPPKTTHWVAI 116

  Fly   145 VRRGRCTFEEKVKHVYQQNAAGVIIYNDKQVMQLEKMQIKGKTRNIAAVITYQNIGQDLSLTLDK 209
            ::||:|||:||:......||:.|||||:........|..:| |.:|.||:..::.|:::...|:|
Zfish   117 MQRGKCTFKEKILKAAAFNASAVIIYNNNTKEDTVTMAHEG-TGDIVAVMITESFGKEILGFLEK 180

  Fly   210 GYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNL 274
            ...|.:|:|.|.||:.  .::||.|::|||||||||||||..|||||:||:.|...|:|:..|.|
Zfish   181 NQTVLVSVIVGSRGMP--KNINRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRL 243

  Fly   275 CSVTKKAIMKIPTKTGKFSD-EKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHR 338
            ....||||.|:.|:|.|..| |.:.|.:.||:|||.|:..|.:|||||||.|||.|:||||.||.
Zfish   244 GDAAKKAISKLTTRTVKRGDKETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPWLNEHC 308

  Fly   339 TCPMCKLDVLKFYG 352
            |||||||::||..|
Zfish   309 TCPMCKLNILKALG 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	41/145 (28%)
		UPF0233	226..>258	CDD:299753	21/31 (68%)
		zf-RING_2	301..344	CDD:290367	28/42 (67%)
rnf130	XP_009289393.1	PA_GRAIL_like	49..188	CDD:239037	41/145 (28%)
rnf130	XP_009289393.1	zf-RING_2	271..314	CDD:290367	28/42 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I8064
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3559
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		otm24367
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	10.070