DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and Znrf3

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001074393.1	Gene:	Znrf3 / 407821	MGIID:	3039616	Length:	913	Species:	Mus musculus

Alignment Length:	331	Identity:	80/331 - (24%)
Similarity:	142/331 - (42%)	Gaps:	88/331 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 SDDYACTPYIRG------TLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYNDKQV 175
            |.||  |.:..|      ..||.:..:||. :.:...|.|...:: :.:|:....||:.....::
Mouse    68 SGDY--TTHTTGLTGRFSRAGAMLSAEGEI-VQMHPLGLCNNNDE-EDLYEYGWVGVVKLEQPEL 128

  Fly   176 MQLEKMQIKGKT-----RNIAAVITYQNIGQDLSLTLDKG----YNVTISIIEGRRGVRTISSLN 231
            .....:.:.||.     |...|||...:...:....|::|    ....:..::|...::.::.:|
Mouse   129 DPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPVVYVKGADAIKLMNIVN 193

  Fly   232 RTSV------------------LFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVT 278
            :..|                  :.:.::|.|  ::|||.||.  :.:.:..|.:.|.|.|..:|
Mouse   194 KQKVARARIQHLPPRQPTEYFDMGIFLAFFV--VVSLVCLIL--LVKIKLKQRRSQNSMNRLAV- 253

  Fly   279 KKAIMKIPTKTGKFSDEKD---------LD-------SDCCAICIEAYKPTDTIRILPCKHEFHK 327
             :|:.|:.|:  ||:.:..         ||       || ||||:|.|...:.:|::||.|.||:
Mouse   254 -QALEKMETR--KFNSKSKGRREGSCGALDTLSSGSTSD-CAICLEKYIDGEELRVIPCTHRFHR 314

  Fly   328 NCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESILEYQPDPPQGLALVEARDESADLNRSRDFV 392
            .|:||||::|.|||.|:               .:|:|.:.:|  |...|    |:::|.|.|.
Mouse   315 KCVDPWLLQHHTCPHCR---------------HNIIEQKGNP--GAVCV----ETSNLTRGRQ-- 356

  Fly   393 VDFPRV 398
               |||
Mouse   357 ---PRV 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	22/114 (19%)
		UPF0233	226..>258	CDD:299753	9/49 (18%)
		zf-RING_2	301..344	CDD:290367	22/42 (52%)
Znrf3	NP_001074393.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		zf-RING_2	289..331	CDD:290367	22/42 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	601..669
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	855..913
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920