DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and 4930595M18Rik

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_775611.2	Gene:	4930595M18Rik / 245492	MGIID:	3045300	Length:	829	Species:	Mus musculus

Alignment Length:	339	Identity:	62/339 - (18%)
Similarity:	121/339 - (35%)	Gaps:	61/339 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 NGTHSFSGMEDRIAVDVYN--YAFLNWSYVEH-----------GNMLCNMEFAQEQARYGEGKVL 101
            :.:|:|..:.|.:|:....  |.|.::..:||           ...:...:|...:....|....
Mouse   503 SNSHTFLPLRDNLAISELQKLYFFPSFPTIEHILTESTAHRSQSTSVTPTKFTTVEIDQKEHTKT 567

  Fly   102 NVTGRLIHITATDNFSDDYACTPYIRGTL-GAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAA 165
            :.......|..:|..|||......:..|: .||....|.     :..|....::.......|:..
Mouse   568 SSCSNQTDIQISDVISDDETLNTNLECTIPSAPCETSGN-----IMLGVFEVDDNFTEFDLQSCD 627

  Fly   166 GVIIYNDKQV-------------MQLEKMQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISI 217
            .:...|:::|             :............::.:::.|......:|.|.|       :|
Mouse   628 SLSSQNNRRVHSGHSRISRSVSSLNSNSTTSSSTNHSLLSLLNYSQQFLPVSSTSD-------NI 685

  Fly   218 IEGRRGVRTISSLNRTS---VLFVSISFIVLMIISLV----------WLIFYYIQRFRYMQAKDQ 269
            |.....:...|.:|:.|   ::|....|.....:.:.          |.:......|     .|.
Mouse   686 IGNDINLPHTSQINQESNEFIVFNCPPFEARQQMHVTSPETSNDSDYWPVLPDFSNF-----NDI 745

  Fly   270 QSRNLCSVTKKAIMKIPTKTGKFSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWL 334
            .:.:...:|::.|..:|..  .|.:..::..  |:||:..|.....||:|||.||:|..|||.||
Mouse   746 HNNHPKGLTEEQINNLPVI--YFCENDEISH--CSICLTQYIKNSKIRVLPCFHEYHDKCIDRWL 806

  Fly   335 IEHRTCPMCKLDVL 348
            .::.|||:|:..::
Mouse   807 SDNSTCPICRKHII 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	21/168 (13%)
		UPF0233	226..>258	CDD:299753	6/44 (14%)
		zf-RING_2	301..344	CDD:290367	20/42 (48%)
4930595M18Rik	NP_775611.2	RRM	<14..176	CDD:223796
		RRM_SF	16..88	CDD:302621
		zf-RING_2	775..816	CDD:290367	20/40 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920