DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and Rnf13

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001106884.1	Gene:	Rnf13 / 24017	MGIID:	1346341	Length:	381	Species:	Mus musculus

Alignment Length:	395	Identity:	102/395 - (25%)
Similarity:	158/395 - (40%)	Gaps:	111/395 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 GMEDRIAVDVYN------YAFLNWSYVEHGNMLCNMEFAQE-----QARYG-----EGKVLNVTG 105
            ||....|..||.      :||||...||...:..|.|.|.:     .||:|     ||    :.|
Mouse     6 GMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFEDLPARFGYRLPAEG----LKG 66

  Fly   106 RLIHITATDNFSDDYACTPYIRGTLGAPIPDKGE-TWIALVRRGRCTFEEKVKHVYQQNAAGVII 169
            .||      |...:.||.|.:    ..|:.|... |:|.|:||..|.|:.||.:..:......|:
Mouse    67 FLI------NSKPENACEPIV----PPPLKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIV 121

  Fly   170 YN----------DKQVMQLEKMQI------KGKTRNIAAVITYQNIGQ-----DLSLTLDKGYNV 213
            :|          ...:..|:|:.|      :....::....||:..|.     :|||.|:
Mouse   122 HNVDSDDLISMGSNDIDTLKKIDIPSVFIGESSANSLKDEFTYEKGGHIILVPELSLPLE----- 181

  Fly   214 TISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVT 278
                                   :..|.|::::.|.|:.::.:.|.:|  :|.:.:..||  .:.
Mouse   182 -----------------------YYLIPFLIIVGICLILIVIFMITKF--VQDRHRNRRN--RLR 219

  Fly   279 KKAIMKIPTKTGKFSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIE-HRTCPM 342
            |..:.|:|....|..||.|:    ||||:|.|:..|.:|||||.|.:|..|:||||.: .:|||:
Mouse   220 KDQLKKLPVHKFKKGDEYDV----CAICLEEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPV 280

  Fly   343 CKLDVLKFYGYVFLGSEES-----ILEYQP-DPPQGLA----------------LVEARDESADL 385
            ||..|:...|.....::.|     :.|:.| .||...|                :.|:.|...|.
Mouse   281 CKQKVVPSQGDSDSDTDSSQEENQVSEHTPLLPPSASARTQSFGSLSESHSHHNMTESSDYEDDD 345

  Fly   386 NRSRD 390
            |...|
Mouse   346 NEETD 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	41/175 (23%)
		UPF0233	226..>258	CDD:299753	4/31 (13%)
		zf-RING_2	301..344	CDD:290367	22/43 (51%)
Rnf13	NP_001106884.1	PA_C_RZF_like	23..180	CDD:239038	43/170 (25%)
		RING-H2_RNF167	238..283	CDD:319711	24/48 (50%)
		RING-H2 finger (C3H2C3-type)	240..281	CDD:319711	22/40 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	285..381		13/66 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920