Protein Alignment gol and Traip

DIOPT Version :10

• Sequence 1: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_035764.2
• Gene: Traip / 22036
• MGIID: 1096377
• Length: 470
• Species: Mus musculus
• Alignment Length: 313
• Identity: 72/313 - (23%)
• Similarity: 111/313 - (35%)
• Gaps: 85/313 - (27%)

  Fly   303 CAICIEAYKPTDTIRILPCKHEFHKNCIDPWL--IEHRTCPMCKLDVLK-------FYGYVFLGS 358
            |.||.:.:..:..:..:.|.|.||..|:..|.  ...||||.|::.|.|       |:.  ....
Mouse     7 CTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFFD--LAQE 69

  Fly   359 EESILE---------------YQPDPPQGLALVEARDESADLNRSRDFVVDFPRVFVLDSGCVVG 408
            ||::|:               .|.|.       |.||..|.::..||
Mouse    70 EENVLDAEFLKNELDSVKAQLSQKDR-------EKRDSQAIIDTLRD------------------ 109

  Fly   409 AREMLFPCRIPERSQSSLSLRQARDWVSLMSNKLEEQQGLRSMRNDEMQQQLLSARESARHRRSR 473
                    .:.||:.:..||:.|.:...::.:.|::|......|.||.:|    |||.| ||..
Mouse   110 --------TLEERNATVESLQNALNKAEMLCSTLKKQMKFLEQRQDETKQ----AREEA-HRLK- 160

  Fly   474 SADGRYSTGCFGGRQRQPSVLVSSLGQPQLHSEVAQMQRSN--SSQALKHLTDAAHAQSRQRQRE 536
                     |......|..:|:.|     ..|||.:|.|..  ...|::.|  |.:..|.:::.|
Mouse   161 ---------CKMKTMEQIELLLQS-----QRSEVEEMIRDMGVGQSAVEQL--AVYCVSLKKEYE 209

  Fly   537 SFDFAR--TRRRFMRRESDEISLRSLPRRGATSAAHRQLHREREPDDSVHTDQ 587
            :...||  |.....|.:.|.:|.||..:...|.....:|.......|....||
Mouse   210 NLKEARKATGELADRLKKDLVSSRSKLKTLNTELDQAKLELRSAQKDLQSADQ 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037
		HRD1	<237..>347	CDD:227568	14/45 (31%)
		RING-H2_RNF130-like	302..347	CDD:438330	14/45 (31%)
Traip	NP_035764.2	RING-H2_TRAIP	6..50	CDD:438143	13/42 (31%)
		EnvC	65..>279	CDD:443969	55/255 (22%)
		Interaction with CYLD. /evidence=ECO:0000250|UniProtKB:Q9BWF2	211..470		13/52 (25%)
		PIP-box. /evidence=ECO:0000250|UniProtKB:Q9BWF2	461..470