DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and Rlim

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001345134.1	Gene:	Rlim / 19820	MGIID:	1342291	Length:	600	Species:	Mus musculus

Alignment Length:	112	Identity:	38/112 - (33%)
Similarity:	60/112 - (53%)	Gaps:	14/112 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 LIFYYIQRFRYMQAKDQ-QSRNLCSVTKKAIMKIPTKTGKFSDEKDLDSDCCAICIEAYKPTDTI 316
            |.|..:.:|..:...|: |.|.|   ||:.|..:..::  |.:...|.:  |::||..|...:.:
Mouse   502 LPFLSLAQFFLLNEDDEDQPRGL---TKEQIDNLAMRS--FGENDALKT--CSVCITEYTEGNKL 559

  Fly   317 RILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESIL 363
            |.|||.||:|.:|||.||.|:.|||:|:..||.      .|:.||::
Mouse   560 RKLPCSHEYHVHCIDRWLSENSTCPICRRAVLS------SGNRESVV 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037
		UPF0233	226..>258	CDD:299753	2/4 (50%)
		zf-RING_2	301..344	CDD:290367	20/42 (48%)
Rlim	NP_001345134.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	49..355
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	417..497
		RING_Ubox	544..588	CDD:388418	21/45 (47%)
		PDZ-binding. /evidence=ECO:0000255	597..600		2/2 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920