DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment gol and H10E21.5

DIOPT Version :9

Sequence 1:NP_001163300.1 Gene:gol / 38006 FlyBaseID:FBgn0004919 Length:601 Species:Drosophila melanogaster
Sequence 2:NP_497129.1 Gene:H10E21.5 / 175169 WormBaseID:WBGene00019185 Length:473 Species:Caenorhabditis elegans


Alignment Length:348 Identity:119/348 - (34%)
Similarity:161/348 - (46%) Gaps:86/348 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   227 ISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGK 291
            :.|.::|||||||||||:||:|||.||:|||:|||||..|||:..|.|.:..:||:.:|||.|..
 Worm   152 LRSFSKTSVLFVSISFIILMVISLAWLVFYYVQRFRYAHAKDRLQRRLFNAARKALTRIPTMTIT 216

  Fly   292 FSDEKDLDSDCCAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYGYVFL 356
            ....::|.|| ||:|::.|:..|.||:|||||.:||:||||||:|||||||||.|:||.:||   
 Worm   217 PGMTQELQSD-CAVCLDPYQLQDVIRLLPCKHIYHKSCIDPWLLEHRTCPMCKNDILKHFGY--- 277

  Fly   357 GSEESILEYQPDPPQGLALVEARDESADLNRSRDFVVDFPRVFVLDSGCVVGAREMLFPCRIPER 421
                              ..:.|::......||....||.....|      |.:|...|      
 Worm   278 ------------------WNDIRNDIQMPTNSRGIADDFTIRLEL------GEQEHQAP------ 312

  Fly   422 SQSSLSLRQARDWVSLMSNK-LEEQQGLRSMRNDEMQQQLLSARESARHRRSRSADGRYSTGCFG 485
                     :.|.:|..:|. ..:.||. |..|.|             |..|.|..  |.|    
 Worm   313 ---------SADVISPEANSDTSDSQGF-SFDNSE-------------HHHSESFG--YGT---- 348

  Fly   486 GRQRQPSVLVSSLGQPQLHSEVAQMQRSNSSQALKHLTDAAHAQSRQRQRESFDFARTRRRFMRR 550
                      ||...|||     .:..||:...:..|:....:|..|..|: |..||..|     
 Worm   349 ----------SSTVPPQL-----VLNASNAKSFVMPLSSRGVSQGPQASRD-FRSARAPR----- 392

  Fly   551 ESDEISLRSLPRRGATSAAHRQL 573
             ....||..|||...::|:..|:
 Worm   393 -DHRASLHELPRPQTSAASQGQI 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
golNP_001163300.1 PA_GRAIL_like 73..217 CDD:239037
UPF0233 226..>258 CDD:299753 21/30 (70%)
zf-RING_2 301..344 CDD:290367 28/42 (67%)
H10E21.5NP_497129.1 HRD1 <150..325 CDD:227568 87/215 (40%)
RING-H2_GRAIL 226..273 CDD:319582 31/47 (66%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C160158743
Domainoid 1 1.000 81 1.000 Domainoid score I5497
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S3321
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000832
OrthoInspector 1 1.000 - - oto17963
orthoMCL 1 0.900 - - OOG6_107948
Panther 1 1.100 - - LDO PTHR22765
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3602
SonicParanoid 1 1.000 - - X295
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1211.780

Return to query results.
Submit another query.