Protein Alignment gol and gzl

DIOPT Version :10

• Sequence 1: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_061507994.1
• Gene: gzl / 1281089
• VectorBaseID: AGAMI1_008543
• Length: 618
• Species: Anopheles gambiae
• Alignment Length: 576
• Identity: 129/576 - (22%)
• Similarity: 209/576 - (36%)
• Gaps: 133/576 - (23%)

  Fly    62 IAVDVYNYAFLNWSYVEHGNMLCNMEFAQEQARYGEGKVLNVTGRLIHITATDNFSDDYACTPYI 126
            :..|:..|..||...:|        ||....|.:| |::.:...:::    .|.......||..
Mosquito    52 VRADILVYQMLNDQIIE--------EFRDLPATFG-GEIPDSGLKVL----ADRADPPDGCTEM- 102

  Fly   127 RGTLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIY----NDKQVMQLEKMQ----- 182
                 .|.|:....:..::.|..|:||.||::..|...|.||::    ||.:.|.....|
Mosquito   103 -----RPAPNITSKFAVVIARYNCSFEVKVRNAQQAGYAMVIVHNVGSNDLEHMSANHPQDLLIP 162

  Fly   183 --IKGKT--RNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFI 243
              ..|::  |:|.....|.: ...|.:|.|..:|::.::|             ....:.|.:.||
Mosquito   163 SVFVGESAGRSIIEAYLYDH-DYALVITDDIPFNISNNLI-------------IPFAIVVGLCFI 213

  Fly   244 VLMIISLVWLIFYYI-QRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSDEKDLDSDCCAICI 307
            ::.::.::::|...| :|.|.|:.:         :..:.:.||    |.....|.:..|.||||:
Mosquito   214 IMRVLQVLFMIIRCIRERRRRMRHR---------LPARVLRKI----GIVKFAKGMRFDTCAICL 265

  Fly   308 EAYKPTDTIRILPCKHEFHKNCIDPWLIEH-RTCPMCKLDVLKFYGYVFLGSEESILEYQPDPPQ 371
            |.:...:.:|:|||:|.:|..||||||.:: |.||:||..|:       :..|.....|..|
Mosquito   266 EDFVENERLRVLPCRHAYHAICIDPWLTKNRRVCPICKRRVI-------VRGEARQRRYSSD--- 320

  Fly   372 GLALVEARDESADLNRSRD--------FVVDFP---------RVFVLDSGCVVGAREMLFPCRIP 419
            .::...| |||..|..|.:        .||..|         ...|..|| ..||.........|
Mosquito   321 SMSSTNA-DESTPLLNSTENSTSGSAAGVVTAPPATSSSSPVTAAVAPSG-NSGAGAQTAAAAAP 383

  Fly   420 ERSQSSLSLRQARDWVSLMSNKLEEQQGLRSMRNDEMQQQLLSARESARHRRSRSA--------D 476
            :|.|..|....|.|...:.....::...:...||....:.||..|.|::.:..:..        :
Mosquito   384 QREQQQLQQNAAPDSHVMEVPPSDDDDEMLDDRNVPSARWLLRGRTSSQQQHQQQQQPQQQPLNE 448

  Fly   477 GRYSTGCFGGRQRQPS-------VLVSSLGQ-------------------PQLHSEVAQMQRSNS 515
            ..||.  .|.....||       ....|..|                   ||..|....:...|:
Mosquito   449 SPYSP--IGDNVATPSRWRFFQRFFTRSTAQSDTEGNNIQEPPAPAQAPSPQPFSPTVPLGTGNN 511

  Fly   516 SQALKHLTDAAHAQSRQRQRESFDFARTRRRFMRRESDEISLRSLPRRGATSAAHR 571
            . ...||:.:.|........|..| |..|.|..:|:     .||.|...:||...|
Mosquito   512 I-LNAHLSGSFHGSEDTTDDELLD-AMQRDRTKQRQ-----FRSAPDMPSTSVGAR 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	34/156 (22%)
		HRD1	<237..>347	CDD:227568	35/111 (32%)
		RING-H2_RNF130-like	302..347	CDD:438330	22/45 (49%)
gzl	XP_061507994.1	None