DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gol and rnf150

DIOPT Version :9

Sequence 1:	NP_001163300.1	Gene:	gol / 38006	FlyBaseID:	FBgn0004919	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001135553.1	Gene:	rnf150 / 100216098	XenbaseID:	XB-GENE-5993052	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	130/332 - (39%)
Similarity:	190/332 - (57%)	Gaps:	25/332 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 AFLNWSYVEHGNMLCNMEFAQEQARYGEGKVLNVTGRLIHITATDNFSDDYACTPYIRGTLGAPI 134
            ||:|.:|.:..:.....| ..|..||||..:......|..:.::.  .|..||.|..:.:    :
Frog    42 AFVNITYTDPLSHQWRTE-KSECGRYGEHSLKQDAWGLAVMPSSP--QDRLACDPATKFS----V 99

  Fly   135 PDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYN--DKQVMQLEKMQIKGKTRNIAAVITYQ 197
            |.....|:||:.:|.||:.:|:||...|||:.|:|||  .....:...|...| ..:|.|::..:
Frog   100 PANASRWVALIPKGNCTYRDKIKHAALQNASAVLIYNVGSSNANETITMPHPG-IEDIVAIMIPE 163

  Fly   198 NIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIVLMIISLVWLIFYYIQRFR 262
            ..|::::..|::..||||.|..|.|.::  ..::||||:||||||||||||||.||:||||||||
Frog   164 PKGREIATLLERNINVTIYITIGTRNLQ--KYVSRTSVVFVSISFIVLMIISLAWLVFYYIQRFR 226

  Fly   263 YMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSD-EKDLDSDCCAICIEAYKPTDTIRILPCKHEFH 326
            |..|:|:..|.|....||||.|:..:|.|..| |.:.:.|.||:|||.|||.|.:|||||:|.||
Frog   227 YANARDRNQRRLGDAAKKAISKLQVRTIKKGDKETEPEFDNCAVCIEGYKPNDVVRILPCRHLFH 291

  Fly   327 KNCIDPWLIEHRTCPMCKLDVLKFYGYVFLGSEESILEYQPD------PP----QGLALVEARDE 381
            |:|:||||::||||||||:::||..|  ...:.:.:.:..||      ||    .|.:.|...:.
Frog   292 KSCVDPWLLDHRTCPMCKMNILKALG--IPPNADCLDDIPPDFEGSVGPPTNQITGASDVTVNES 354

  Fly   382 SADLNRS 388
            |..::.|
Frog   355 SVGIDPS 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	40/145 (28%)
		UPF0233	226..>258	CDD:299753	22/31 (71%)
		zf-RING_2	301..344	CDD:290367	30/42 (71%)
rnf150	NP_001135553.1	PA_GRAIL_like	45..183	CDD:239037	40/145 (28%)
		UPF0233	<197..>222	CDD:299753	21/24 (88%)
		zf-RING_2	266..309	CDD:290367	30/42 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	87	1.000	Domainoid score	I7883
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		otm49035
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3602
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100