Protein Alignment gol and rnf130

DIOPT Version :10

• Sequence 1: NP_001163300.1
• Gene: gol / 38006
• FlyBaseID: FBgn0004919
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001107712.1
• Gene: rnf130 / 100124963
• XenbaseID: XB-GENE-949564
• Length: 419
• Species: Xenopus tropicalis
• Alignment Length: 304
• Identity: 123/304 - (40%)
• Similarity: 167/304 - (54%)
• Gaps: 38/304 - (12%)

  Fly    75 SYVEHGNMLCNME-------------------FAQEQARYG------EGKVLNVTGRLIHITATD 114
            |.|:.|:...|||                   ...:..|||      |.|.|.:|...||..|
 Frog    22 SMVQSGSDTANMENYSALVNVTIQDPSSNPVLLRIDGGRYGLDSPKTEAKGLLLTPVHIHGAA-- 84

  Fly   115 NFSDDYACTPYIRGTLGAPIPDKGETWIALVRRGRCTFEEKVKHVYQQNAAGVIIYNDKQVMQLE 179
               |...|.|..|..    :|...:.||||::||.|||:||:......||:.|:|||:....:..
 Frog    85 ---DRLGCDPQTRFN----VPPNTKHWIALLQRGNCTFKEKILRAASHNASAVVIYNNNSKEETV 142

  Fly   180 KMQIKGKTRNIAAVITYQNIGQDLSLTLDKGYNVTISIIEGRRGVRTISSLNRTSVLFVSISFIV 244
            .|..:| |..|.|::..:..|:::...:::..:|.::|..|.|...  .:.:|.|::||||||||
 Frog   143 TMTHQG-TGEIVAIMISEARGREILSYVERNISVLMAIAVGSRNQH--KNFSRGSLVFVSISFIV 204

  Fly   245 LMIISLVWLIFYYIQRFRYMQAKDQQSRNLCSVTKKAIMKIPTKTGKFSD-EKDLDSDCCAICIE 308
            |||||..|||||:||:.||..|:|:..|.|....||||.|:.|:|.|..| |.|.|.|.||:|||
 Frog   205 LMIISSAWLIFYFIQKIRYTSARDRNQRRLGDAAKKAIGKLTTRTVKKGDKETDPDFDHCAVCIE 269

  Fly   309 AYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDVLKFYG 352
            :||..|.:|:|||||.|||.|:||||.||.|||||||::||..|
 Frog   270 SYKQNDIVRVLPCKHVFHKVCVDPWLSEHCTCPMCKLNILKALG 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gol	NP_001163300.1	PA_GRAIL_like	73..217	CDD:239037	45/166 (27%)
		HRD1	<237..>347	CDD:227568	70/110 (64%)
		RING-H2_RNF130-like	302..347	CDD:438330	31/44 (70%)
rnf130	NP_001107712.1	PA_GRAIL_like	41..179	CDD:239037	39/147 (27%)
		HRD1	<197..344	CDD:227568	73/117 (62%)
		RING_Ubox	262..310	CDD:473075	32/47 (68%)