Protein Alignment gsb and ISX

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001290437.1
• Gene: ISX / 91464
• HGNCID: 28084
• Length: 245
• Species: Homo sapiens
• Alignment Length: 181
• Identity: 59/181 - (32%)
• Similarity: 79/181 - (43%)
• Gaps: 47/181 - (25%)

  Fly   125 GVCDKQNAPSVS-SISRLLR--------------GSSGSGTSHSIDGILGGGAGSVGSEDESEDD 174
            |.|:.....|:| ||..:|:              |..|.|.:         .|...|.|...:|.
Human    19 GCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEA---------AASGSGLEKPPKDQ 74

  Fly   175 AEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRAR 239
            .:..   ::.:||.||||:.:|:..||:||..|.||||:.|.:||....|.|||||:||.|:||:
Human    75 PQEG---RKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAK 136

  Fly   240 LRKQ-----LNTQQVPSFA------------PTSTSFG---ATPTTSAAPA 270
            .|||     |...|..|.|            ||.||..   ..|.||..|:
Human   137 WRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAPPTSCCPS 187

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	6/18 (33%)
		Homeodomain	186..242	CDD:459649	30/55 (55%)
ISX	NP_001290437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..86		9/59 (15%)
		Homeodomain	83..139	CDD:459649	30/55 (55%)