Protein Alignment gsb and Isx

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001387929.1
• Gene: Isx / 682968
• RGDID: 1592776
• Length: 242
• Species: Rattus norvegicus
• Alignment Length: 270
• Identity: 80/270 - (29%)
• Similarity: 112/270 - (41%)
• Gaps: 83/270 - (30%)

  Fly   137 SISRLLRGSSG-------SGTSHSIDGIL---------------GGG----AGSVGSEDESEDDA 175
            :|.|.:..|||       .|.|.||:.||               |||    ..:.||:.|.....
  Rat     5 TIQRDIEKSSGYCEAPEKLGLSFSIEAILKRPTERRNLPRPQSIGGGDSRQTTTSGSKLEKPTQD 69

  Fly   176 EPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARL 240
            :|..:.|.| ||.||||:.:|:..||::|..|.|||::.|.:||....|.|||||:||.|:||:.
  Rat    70 QPQEERKNK-RRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKW 133

  Fly   241 RKQ-----LNTQQVP---SFAPTSTSFGAT-----PTTSAA-----PAPN-------MGMSLYSS 280
            |||     |:..|.|   :.|..|...|||     |.:.:|     |.|:       ||
  Rat   134 RKQEKSGSLSAPQQPGSCTDAHCSAHIGATHRMLPPLSDSARFKLVPCPDSPCPMAPMG------ 192

  Fly   281 QSWPSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQQPGTGSEFMTSTYGVGSSNAT 345
               |::.|:.:|.      |::.|         ..|.|    ..:|..|.....:....|.|
  Rat   193 ---PAAPAWPSHP------AALCP---------YLHPP----TPKPQVGQHLCNANIRTGFS--- 232

  Fly   346 YPSAAYSMPQ 355
            .|..|..:||
  Rat   233 LPKQATLLPQ 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	2/5 (40%)
		Homeodomain	186..242	CDD:459649	28/55 (51%)
Isx	NP_001387929.1	Homeodomain	79..135	CDD:459649	28/55 (51%)