Protein Alignment gsb and pax6b

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: XP_005168876.1
• Gene: pax6b / 60639
• ZFINID: ZDB-GENE-001031-1
• Length: 450
• Species: Danio rerio
• Alignment Length: 430
• Identity: 169/430 - (39%)
• Similarity: 222/430 - (51%)
• Gaps: 91/430 - (21%)

  Fly    23 VNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLR-------------VSHGCVSKILNR 74
            ||||||||:||||||:..|::|||:|.:|.|||.|||.|:             ||:|||||||.|
Zfish    27 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHDDAKVQLDNKNVSNGCVSKILGR 91

  Fly    75 FQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSIS 139
            :.|||||||..|||||||||||::..:|.:.|:..|.||:||||.:|:..|||...|.||||||:
Zfish    92 YYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSIN 156

  Fly   140 RLLR----------------------GSSGS---------GTS----HSIDGIL-----GGGAGS 164
            |:||                      |.||:         |||    .:.||..     |....|
Zfish   157 RVLRNLASEKQQMGADGMYDKLRMLNGQSGTWGTRPGWYPGTSVPGQPNQDGCQQQDNGGENTNS 221

  Fly   165 VGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARV 229
            :.|..|..|:.:..:|||||.:|:||:|:.:||:|||:.|.||.||||:.||.||....|.|||:
Zfish   222 ISSNGEDSDETQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARI 286

  Fly   230 QVWFSNRRARLRKQ--LNTQQ-----VPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQ------ 281
            |||||||||:.|::  |..|:     ..|..|.|:||. |....|.|.|...:|..:..
Zfish   287 QVWFSNRRAKWRREEKLRNQRRQASNSSSHIPISSSFN-TSVYQAIPQPTTPVSFTTGSMLGRPD 350

  Fly   282 -----------SWPSSGAYEN---HAAYGGSVASMSPAS-STSGTSSAAHSPVQTQAQQPGTGSE 331
                       ..||.....|   ..:...|.:.|.|:| |.:|.|...::|...||..   .|:
Zfish   351 TALTNTYTGLPPMPSFTMANNLPMQPSQTSSYSCMLPSSPSVNGRSFDTYTPPHMQAHM---NSQ 412

  Fly   332 FMTSTYGVGSSNATYPSAAYSMP-QTPATSAEQLRSQFAS 370
            .| :|.|..|:....|..  |:| |.|.|..:.  ||:.|
Zfish   413 TM-ATSGTASTGLISPGV--SVPVQVPGTEPDM--SQYWS 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	76/132 (58%)
		Homeodomain	186..242	CDD:459649	33/55 (60%)
pax6b	XP_005168876.1	PAX	23..160	CDD:128645	76/132 (58%)
		Homeodomain	244..299	CDD:459649	33/54 (61%)