Protein Alignment gsb and PRRX1

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_073207.1
• Gene: PRRX1 / 5396
• HGNCID: 9142
• Length: 245
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 74/228 - (32%)
• Similarity: 106/228 - (46%)
• Gaps: 29/228 - (12%)

  Fly   107 QSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSISRLL-RGSSGSGTSHSIDGILGGGAGSV----- 165
            :.||.     :..:|...|..|...|....|:|.|| ...:|...:...|..:|....|:
Human    10 ERQPA-----LGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADENVGEAGRSLLESPG 69

  Fly   166 ---GSE--DESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLT 225
               ||:  .:..|......:.||||||:||||::.|:.||||:|.||.|||.:.||:||:...||
Human    70 LTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLT 134

  Fly   226 EARVQVWFSNRRARLRK-------QLNTQQVPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSW 283
            ||||||||.||||:.|:       ..|...:.|::...|:.........||.|.      ...||
Human   135 EARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPRPAPRPT------DYLSW 193

  Fly   284 PSSGAYENHAAYGGSVASMSPASSTSGTSSAAH 316
            .::..|...|.|..:.|:.|||...:..:|.|:
Human   194 GTASPYSAMATYSATCANNSPAQGINMANSIAN 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	10/36 (28%)
		Homeodomain	186..242	CDD:459649	35/55 (64%)
PRRX1	NP_073207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		3/16 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..103		14/39 (36%)
		Homeodomain	99..151	CDD:459649	32/51 (63%)
		OAR	219..235	CDD:461067	2/8 (25%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235		2/5 (40%)