Protein Alignment gsb and EVX2

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001073927.1
• Gene: EVX2 / 344191
• HGNCID: 3507
• Length: 476
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 104/412 - (25%)
• Similarity: 156/412 - (37%)
• Gaps: 88/412 - (21%)

  Fly    36 LPNHIRRQIVEMAAAGVRPCVISRQLRVS--HGCVSKI----------LNRFQETGSIRPGVIGG 88
            |.|.....::|.......|..:|.:|..:  |..:.::          |...|.|||
Human    28 LSNSAGNAVLEALENSQHPARLSPRLPSAPLHSALGELPAKGKFEIDTLFNLQHTGS-------- 84

  Fly    89 SKPRVATPDIESRIEELKQSQPGIFSWEIRAKL-----IEAGVCDKQNAPSVSSISRL------- 141
              ....:.:|.|..|..|  :||.:| |..|:.     :|.| |....:|.....::|
Human    85 --ESTVSSEISSAAESRK--KPGHYS-EAAAEADMSSDVEVG-CSALRSPGGLGAAQLKENNGKG 143

  Fly   142 -LRGSSGSGTSHSIDG-----ILGGGAGSVGSE--DESEDDAEPSVQLKRKQRRSRTTFSNDQID 198
             ....|.:||:.|..|     :.||..||.||.  ..|...|:       :.||.||.|:.:||.
Human   144 YAESGSAAGTTTSASGSGLGSLHGGSGGSGGSAALGGSGSGAD-------QVRRYRTAFTREQIA 201

  Fly   199 ALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQLNTQQVPSFAPTSTSFGATP 263
            .||:.|.|..|.....|.|||.:..|.|..::|||.|||.:.::|......|.  |...||....
Human   202 RLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMSWPH--PADPSFYTYM 264

  Fly   264 TTSAAPAPNMGMSLYSS---QSWPSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQ- 324
            .|.||...::....:|.   ..:|..|           |.:.:.|::.||.::||.||..|..:
Human   265 MTHAAATGSLPYPFHSHVPLHYYPHVG-----------VTAAAAAAAASGAAAAASSPFATSIRP 318

  Fly   325 --------QPGTGSEFMTSTYGVGSSNATYPSAAYSMPQTPATSAEQLRSQFASAAASGSHHPST 381
                    .|.:..|.:.|....|...|...:|..:...:.|.:|....:..:||||:|: .||
Human   319 LDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAASAAAAAAAAAAAASSAAAAGA-PPS- 381

  Fly   382 WDSYNFAGSFFPPASAAGNHIS 403
                  .||  .|.|....|.|
Human   382 ------GGS--APCSCLSCHSS 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	26/131 (20%)
		Homeodomain	186..242	CDD:459649	24/55 (44%)
EVX2	NP_001073927.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..113		12/43 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..185		12/42 (29%)
		Homeodomain	189..245	CDD:459649	24/55 (44%)