Protein Alignment gsb and pax6a

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: XP_009296153.1
• Gene: pax6a / 30567
• ZFINID: ZDB-GENE-990415-200
• Length: 459
• Species: Danio rerio
• Alignment Length: 428
• Identity: 170/428 - (39%)
• Similarity: 220/428 - (51%)
• Gaps: 98/428 - (22%)

  Fly    18 QGQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLR--------------VSHGCV 68
            :|...||||||||:||||||:..|::|||:|.:|.|||.|||.|:              ||:|||
Zfish    30 EGHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENVSNGCV 94

  Fly    69 SKILNRFQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAP 133
            ||||.|:.|||||||..|||||||||||::..:|.:.|:..|.||:||||.:|:..|||...|.|
Zfish    95 SKILGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIP 159

  Fly   134 SVSSISRLLR----------------------GSSGS---------GTS----HSIDGIL---GG 160
            |||||:|:||                      |.:|:         |||    .:.||..   ||
Zfish   160 SVSSINRVLRNLASEKQQMGADGMYEKLRMLNGQTGTWGTRPGWYPGTSVPGQPNQDGCQQSDGG 224

  Fly   161 G--AGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTG 223
            |  ..|:.|..|..|:.:..:|||||.:|:||:|:.:||:|||:.|.||.||||:.||.||....
Zfish   225 GENTNSISSNGEDSDETQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKID 289

  Fly   224 LTEARVQVWFSNRRARLRKQ--LNTQQ-----VPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQ 281
            |.|||:|||||||||:.|::  |..|:     ..|..|.|:|| :|......|.|...:|..|
Zfish   290 LPEARIQVWFSNRRAKWRREEKLRNQRRQASNSSSHIPISSSF-STSVYQPIPQPTTPVSFTS-- 351

  Fly   282 SWPSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQA----QQPGTGSEFM----TSTYG 338
                           ||:...|..:.|:..|:....|..|.|    .||...|.:.    ||...
Zfish   352 ---------------GSMLGRSDTALTNTYSALPPMPSFTMANNLPMQPSQTSSYSCMLPTSPSV 401

  Fly   339 VGSSNATYPSAAYSMPQTPATSAEQLRSQFASAAASGS 376
            .|.|..||         ||......:.||  |.||||:
Zfish   402 NGRSYDTY---------TPPHMQAHMNSQ--SMAASGT 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	77/137 (56%)
		Homeodomain	186..242	CDD:459649	33/55 (60%)
pax6a	XP_009296153.1	PAX	31..169	CDD:128645	77/137 (56%)
		Homeodomain	253..308	CDD:459649	33/54 (61%)