Protein Alignment gsb and pax3a

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 503
• Identity: 208/503 - (41%)
• Similarity: 260/503 - (51%)
• Gaps: 118/503 - (23%)

  Fly    13 GGYPFQ-----GQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKIL 72
            |||..:     |||||||||||||||||||||||.:|||||..|:||||||||||||||||||||
Zfish    23 GGYSLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKIL 87

  Fly    73 NRFQETGSIRPGVIGGSKPRVA-TPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVS 136
            .|:|||||||||.||||||:.: |||:|.:|||.|:..||:||||||.||::.|:||:.|.||||
Zfish    88 CRYQETGSIRPGAIGGSKPKQSTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDGICDRNNVPSVS 152

  Fly   137 SISRLLR---GSSGS------------------GTSHSIDGILGGGAGSVGSEDESEDDAEPSVQ 180
            ||||:||   |.:|.                  ...||||||||.  .|..|::.|:.|:||.:.
Zfish   153 SISRMLRCKFGGNGDEDEDDDEVEKREIEENERRAKHSIDGILGD--RSSHSDEGSDVDSEPGLP 215

  Fly   181 LKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQLN 245
            ||||||||||||:.:|::.|||.|.||.|||:||||||||...||||||||||||||||.|||..
Zfish   216 LKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAG 280

  Fly   246 TQQVPSF--------------------------APTSTS-FGATPTTSAAPAPNMGMSLYSSQSW 283
            ..|:.:|                          .|:|.| ....|:|...|.|....|::.|...
Zfish   281 ANQLMAFNHLIPGGFPPSAMSSLQPYQLADSPYPPSSISQVSEQPSTVHRPQPLPPTSVHQSGLG 345

  Fly   284 PSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQQPGTGSEFMTSTYGVGSSNATYPS 348
            ...||.|..:||       ..:|...|.|..:...|...                 |.:|...||
Zfish   346 SGPGAQEGSSAY-------CLSSGRHGFSGYSDGYVAAP-----------------GHANPVNPS 386

  Fly   349 AAYSMPQ------TPATSAEQLRSQFASAAASGSHHPSTW------------------------D 383
            .:..:|.      .|.....|.:|.||.:..:|...|||.                        .
Zfish   387 ISNGLPSQVMGLLNPGAVPHQPQSDFALSPLTGGLEPSTGMPASCHSSQRLEALPGLPSMPALPS 451

  Fly   384 SYNFAGSFFPPASAAGNHISGYHHQVDQKSSMMTTAPT--------YP 423
            |.::..|.:.....:.:|::.|.:....:|.:.|:..|        ||
Zfish   452 SQSYCPSSYSSPGYSVDHVASYQYSQYGQSKVNTSTVTTVERLSRVYP 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	95/124 (77%)
		Homeodomain	186..242	CDD:459649	41/55 (75%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	95/124 (77%)
		Homeodomain	221..277	CDD:459649	41/55 (75%)
		Pax7	350..394	CDD:403540	13/67 (19%)