Protein Alignment gsb and Pitx3

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_062120.1
• Gene: Pitx3 / 29609
• RGDID: 3332
• Length: 302
• Species: Rattus norvegicus
• Alignment Length: 234
• Identity: 81/234 - (34%)
• Similarity: 107/234 - (45%)
• Gaps: 30/234 - (12%)

  Fly   163 GSVGSEDESEDDAEPSV--------QLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELA 219
            |..|.|....:.|..|:        .||:||||.||.|::.|:..||..|.|.:|||:.||||:|
  Rat    32 GCKGQEHSDSEKASASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIA 96

  Fly   220 QSTGLTEARVQVWFSNRRARLRKQLNTQQVPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSWP 284
            ..|.||||||:|||.||||:.||:..:||    |.......|.|.....|........|:..:||
  Rat    97 VWTNLTEARVRVWFKNRRAKWRKRERSQQ----AELCKGGFAAPLGGLVPPYEEVYPGYTYGNWP 157

  Fly   285 SSGAYENHAA----YGGSVASMSPASST---SGTSSAAHSPVQTQAQQPGT--GSEFMTSTYGV- 339
            ........||    :..:..::.|.:|.   |..||.|.|.|.:.|..|||  |...:....|.
  Rat   158 PKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPGPGALQGLGGAP 222

  Fly   340 -GSSNATYPSAAYSMPQTPATSAEQLRSQFASAAASGSH 377
             |.:.|...|.|.|.|...|.:|       |:||||..:
  Rat   223 PGLAPAAVSSGAVSCPYASAAAA-------AAAAASSPY 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645
		Homeodomain	186..242	CDD:459649	32/55 (58%)
Pitx3	NP_062120.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		14/38 (37%)
		Homeodomain	63..119	CDD:459649	32/55 (58%)
		PTZ00395	<142..>236	CDD:185594	24/93 (26%)
		OAR	258..275	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	262..275
		Nuclear localization signal. /evidence=ECO:0000255	268..272