Protein Alignment gsb and Pax2

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: XP_006231505.2
• Gene: Pax2 / 293992
• RGDID: 1305568
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 456
• Identity: 149/456 - (32%)
• Similarity: 205/456 - (44%)
• Gaps: 119/456 - (26%)

  Fly    10 PYFGGYPFQGQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNR 74
            |:...:|  |.|.||||||||:||||||:.:|::|||:|..|||||.||||||||||||||||.|
  Rat     9 PFSAMHP--GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGR 71

  Fly    75 FQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSIS 139
            :.|||||:|||||||||:||||.:..:|.|.|:..|.:|:||||.:|:..|:||....||||||:
  Rat    72 YYETGSIKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSIN 136

  Fly   140 RLLRGS---------SGSGT---------------------------SHSIDGILG--------- 159
            |::|..         .|:||                           |:||:||||
  Rat   137 RIIRTKVQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKR 201

  Fly   160 ---------------GGAG--------SVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALE 201
                           ||.|        .|........|::..|...||..|: .||:..|::||:
  Rat   202 KREEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALD 265

  Fly   202 RIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQLNTQQVPSFAPTSTSFGATPTTS 266
            |:|.|..||||:...|..:|                    :|.|...:|:..|....  ...:.|
  Rat   266 RVFERPSYPDVFQASEHIKS--------------------EQGNEYSLPALTPGLDE--VKSSLS 308

  Fly   267 AAPAPNMGMSLYSSQSWPSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQQPGT--- 328
            |:..|.:|.::..:|::|              |.:....:||:......|.|...|...|.:
  Rat   309 ASTNPELGSNVSGTQTYP--------------VVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLA 359

  Fly   329 ----GSEFMTSTYGVGSSNA-----TYPSAAYSMPQTPATSAEQLRSQFASAAASGSHHPSTWDS 384
                ||||..:.|......|     .:.:.|..||...|.....|.....:.:..|.|.....||
  Rat   360 GMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGAPPLPLLPLPMTATSYRGDHIKLQADS 424

  Fly   385 Y 385
            :
  Rat   425 F 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	81/123 (66%)
		Homeodomain	186..242	CDD:459649	15/55 (27%)
Pax2	XP_006231505.2	PAX	16..140	CDD:128645	81/123 (66%)
		Pax2_C	305..>390	CDD:463563	19/98 (19%)