Protein Alignment gsb and GSC2

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_005306.1
• Gene: GSC2 / 2928
• HGNCID: 4613
• Length: 205
• Species: Homo sapiens
• Alignment Length: 237
• Identity: 64/237 - (27%)
• Similarity: 84/237 - (35%)
• Gaps: 96/237 - (40%)

  Fly    48 AAAG--------VRPCVISRQLRVSHGCVSKILNRFQETGSIRPGVIGGSKPRVAT--PDIESRI 102
            ||||        .|||..|         :..||:...|.          |.|..|.  |....|.
Human     3 AAAGGAASRRGAGRPCPFS---------IEHILSSLPER----------SLPARAACPPQPAGRQ 48

  Fly   103 EELKQSQPGI-------------------------------FSWEIRAKLIEAGVCDKQNAPSVS 136
            ...|..:||.                               .:|.:|.            .|:|.
Human    49 SPAKPEEPGAPEAAPCACCCCCGPRAAPCGPPEAAAGLGARLAWPLRL------------GPAVP 101

  Fly   137 SISRLLRGSSGSGTSHSIDGILGGGAGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALE 201
                 |...:.:|.|.::.|.:|.|:                   :|:.||.||.||.:|:.|||
Human   102 -----LSLGAPAGGSGALPGAVGPGS-------------------QRRTRRHRTIFSEEQLQALE 142

  Fly   202 RIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQ 243
            .:|.:.|||||.|||.||....|.|.||:|||.||||:.|.|
Human   143 ALFVQNQYPDVSTRERLAGRIRLREERVEVWFKNRRAKWRHQ 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	23/135 (17%)
		Homeodomain	186..242	CDD:459649	32/55 (58%)
GSC2	NP_005306.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..58		7/24 (29%)
		Homeodomain	127..183	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	185..205		64/237 (27%)