DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gsb and Mixl1

DIOPT Version :9

Sequence 1:	NP_523863.1	Gene:	gsb / 38005	FlyBaseID:	FBgn0001148	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001099449.1	Gene:	Mixl1 / 289311	RGDID:	1310011	Length:	231	Species:	Rattus norvegicus

Alignment Length:	217	Identity:	64/217 - (29%)
Similarity:	92/217 - (42%)	Gaps:	69/217 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 MAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIRPG--VIGGSKPRVATPDI--ESRIEELKQ 107
            |||||      |:||:.:.|..      |....:..||  ::..::|....|..  :||
  Rat     1 MAAAG------SQQLQFAEGAA------FPTFPAAHPGGQLLPAARPATGLPPAPPDSR------ 47

  Fly   108 SQPGIFSWEIRAKLIEAGVCDKQNAPSVSSI--SRLLRGSSGSGTSHSIDGILGGGAGSVGSEDE 170
                                    ||:.:..  ||..|.::.:.|.....|             .
  Rat    48 ------------------------APAATPCFPSRGPRPAAQTPTGLDPPG-------------P 75

  Fly   171 SEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSN 235
            |:..|.||.    .|||.||:||::|:..||.:|.:|.|||::.||.||..|.|.|:|:||||.|
  Rat    76 SKGSAAPSA----PQRRKRTSFSSEQLQLLELVFRQTMYPDIHLRERLAALTLLPESRIQVWFQN 136

  Fly   236 RRARLRKQLNTQQVPSFAPTST 257
            |||:.|:|..    .||.|.|:
  Rat   137 RRAKSRRQSG----KSFQPLSS 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	20/101 (20%)
gsb	NP_523863.1	homeodomain	186..243	CDD:238039	31/56 (55%)
Mixl1	NP_001099449.1	PRK14971	<2..139	CDD:237874	55/195 (28%)
Mixl1	NP_001099449.1	Homeobox	89..143	CDD:395001	28/53 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810