Protein Alignment gsb and ALX3

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 94/310 - (30%)
• Similarity: 132/310 - (42%)
• Gaps: 73/310 - (23%)

  Fly    72 LNRFQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVS 136
            |.||...|.:.|.:     |..|.|..: .:::|... |.:..........||    ::.....:
Human    48 LTRFPACGPLEPYL-----PEPAKPPAK-YLQDLGPG-PALNGGHFYEGPAEA----EEKTSKAA 101

  Fly   137 SISRL---LRGSSGSGTSHSIDGILGGGAG----------SVGSEDESEDDAEPSVQLKRKQRRS 188
            |..:|   .||....|.|:     |.|..|          |.|..|..|     ..:.|.|:||:
Human   102 SFPQLPLDCRGGPRDGPSN-----LQGSPGPCLASLHLPLSPGLPDSME-----LAKNKSKKRRN 156

  Fly   189 RTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRKQLNTQQVPSFA 253
            |||||..|::.||::|.:|.|||||.||:||..|.||||||||||.||||:.||:....::..
Human   157 RTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQE-- 219

  Fly   254 PTSTSFGATPTTSAAPA---------PNMGMSLYSSQSWPSSGAYENHAAYGGSVASMSPASSTS 309
                  |..|.|:|...         |.:..||::|   |.||:       .|....:||    .
Human   220 ------GRNPFTAAYDISVLPRTDSHPQLQNSLWAS---PGSGS-------PGGPCLVSP----E 264

  Fly   310 GTSSAAHSPVQTQAQQPGTGSEFMTSTYGVGSSNATYPSAAYSMPQTPAT 359
            |..|...||   .:...|:.:.||    ||.:.:|.:| ..||:...|.|
Human   265 GIPSPCMSP---YSHPHGSVAGFM----GVPAPSAAHP-GIYSIHGFPPT 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	14/73 (19%)
		Homeodomain	186..242	CDD:459649	36/55 (65%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		13/66 (20%)
		PRK12323	<13..131	CDD:481241	21/98 (21%)
		Homeodomain	154..210	CDD:459649	36/55 (65%)