Protein Alignment gsb and Otx1

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_037241.2
• Gene: Otx1 / 25646
• RGDID: 3237
• Length: 355
• Species: Rattus norvegicus
• Alignment Length: 300
• Identity: 94/300 - (31%)
• Similarity: 133/300 - (44%)
• Gaps: 69/300 - (23%)

  Fly   161 GAGSVGSEDESEDDAEPSV---QLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQST 222
            |...:|....:.|...|||   ...|||||.||||:..|:|.||.:||:|:|||::.|||:|...
  Rat    11 GMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKI 75

  Fly   223 GLTEARVQVWFSNRRARLRKQL----NTQQVP---SFAPTSTSFGATPTTSAAPAPNMGMSLYSS 280
            .|.|:||||||.||||:.|:|.    .|:..|   ..:|...|.|:..:....| |.:..|..||
  Rat    76 NLPESRVQVWFKNRRAKCRQQQQSGNGTKSRPVKKKSSPVRESSGSESSGQFTP-PAVSSSASSS 139

  Fly   281 QSWPSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQ-QPGTGSEFMTSTYGVGSSNA 344
            .|  :|.|..|.||...:....:|.::.|..|:...|.:.:.|. .||:....::....:|:
  Rat   140 SS--ASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPASVSVPEPLGA--- 199

  Fly   345 TYPSAAYSMPQTPATSAEQLRSQFASAAAS-----------GSHHPSTWDSYNFAG--------- 389
              ||.|..|.::.|..|       |:||||           |..:|:...|| |.|
  Rat   200 --PSNASCMQRSVAAGA-------ATAAASYPMSYGQGGSYGQGYPAPSSSY-FGGVDCSSYLAP 254

  Fly   390 ----------SFFPPASAAGNH------------ISGYHH 407
                      |...|:|.||:|            .||:||
  Rat   255 MHSHHHPHQLSPMAPSSMAGHHHHHPHAHHPLSQSSGHHH 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645
		Homeodomain	186..242	CDD:459649	32/55 (58%)
Otx1	NP_037241.2	Homeodomain	39..95	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	92..144		13/54 (24%)
		TF_Otx	178..274	CDD:427350	24/108 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..306		9/37 (24%)