Protein Alignment gsb and Shox2

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_037160.2
• Gene: Shox2 / 25546
• RGDID: 3674
• Length: 331
• Species: Rattus norvegicus
• Alignment Length: 335
• Identity: 91/335 - (27%)
• Similarity: 134/335 - (40%)
• Gaps: 100/335 - (29%)

  Fly    99 ESRIEELKQS----------------QPGIFSWEIRAKLIEAGVCDKQNAPSVSSISRLLRGSSG 147
            :.:::|.|::                :||         .:|.| .|.:::|:|    |...|..|
  Rat    13 DQKVKEKKEAITYREVLESGPLRGAKEPG---------CVEPG-RDDRSSPAV----RAAGGGGG 63

  Fly   148 SGTSHSIDGILGGGAGSVGS-------------------------------------EDESED-- 173
            :|......|..|||||..|:                                     :|..||
  Rat    64 AGGGGGGGGGGGGGAGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPELKDRKEDAK 128

  Fly   174 DAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQVWFSNRRA 238
            ..|...|.|.|||||||.|:.:|::.|||:|..|.|||.:.||||:|..||:||||||||.||||
  Rat   129 GMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRA 193

  Fly   239 RLRKQLNTQQVPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSWPSSGAYENHAAYGGSVASMS 303
            :.|||.|..........::.|.|   ...||..|:|......|.       ::|       .:::
  Rat   194 KCRKQENQLHKGVLIGAASQFEA---CRVAPYVNVGALRMPFQQ-------DSH-------CNVT 241

  Fly   304 PASSTSGTSSAAHSPVQTQAQQPGTGSEFMTSTYGVGSSNATY---PSAAYSMP-QTPATSAEQL 364
            |.|          ..||.|.|.....:......:...:::|.|   |:..:.:| .|.|..:...
  Rat   242 PLS----------FQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFPAPPFGLPLATLAADSASA 296

  Fly   365 RSQFASAAAS 374
            .|..|:|||:
  Rat   297 ASVVAAAAAA 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	10/59 (17%)
		Homeodomain	186..242	CDD:459649	34/55 (62%)
Shox2	NP_037160.2	Homeodomain	141..197	CDD:459649	34/55 (62%)
		OAR	311..327	CDD:461067