Protein Alignment gsb and Pax6

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: XP_006234695.1
• Gene: Pax6 / 25509
• RGDID: 3258
• Length: 436
• Species: Rattus norvegicus
• Alignment Length: 464
• Identity: 170/464 - (36%)
• Similarity: 229/464 - (49%)
• Gaps: 131/464 - (28%)

  Fly    23 VNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLR--------------VSHGCVSKILN 73
            ||||||||:||||||:..|::|||:|.:|.|||.|||.|:              ||:|||||||.
  Rat     8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDSENVSNGCVSKILG 72

  Fly    74 RFQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSI 138
            |:.|||||||..|||||||||||::.|:|.:.|:..|.||:||||.:|:..|||...|.||||||
  Rat    73 RYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSI 137

  Fly   139 SRLLR----------------------GSSGS---------GTS----HSIDGI-----LGGGAG 163
            :|:||                      |.:||         |||    .:.||.     .|....
  Rat   138 NRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGQGENTN 202

  Fly   164 SVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEAR 228
            |:.|..|..|:|:..:|||||.:|:||:|:.:||:|||:.|.||.||||:.||.||....|.|||
  Rat   203 SISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEAR 267

  Fly   229 VQVWFSNRRARLRKQ--LNTQQ-----VPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSWPSS 286
            :|||||||||:.|::  |..|:     .||..|.|:|| :|......|.|...:|.::|
  Rat   268 IQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSF-STSVYQPIPQPTTPVSSFTS------ 325

  Fly   287 GAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQA----QQPGTGSEFMTSTYGVGSSNATYP 347
                      ||:...:..:.|:..|:....|..|.|    .||...|:  ||:|
  Rat   326 ----------GSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQ--TSSY---------- 368

  Fly   348 SAAYSMPQTPATSAEQLRSQFASAAASGSHHPSTWDSYNFAGSFFPPASAAGNHISGYHHQVDQK 412
              :..:|.:|:.:..                  ::|:|.      ||           |.|....
  Rat   369 --SCMLPTSPSVNGR------------------SYDTYT------PP-----------HMQTHMN 396

  Fly   413 SSMMTTAPT 421
            |..|.|:.|
  Rat   397 SQPMGTSGT 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	77/133 (58%)
		Homeodomain	186..242	CDD:459649	33/55 (60%)
Pax6	XP_006234695.1	PAX	4..142	CDD:128645	77/133 (58%)
		Homeodomain	226..281	CDD:459649	33/54 (61%)