Protein Alignment gsb and Pax8

DIOPT Version :9

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_035170.1
• Gene: Pax8 / 18510
• MGIID: 97492
• Length: 457
• Species: Mus musculus
• Alignment Length: 489
• Identity: 155/489 - (31%)
• Similarity: 220/489 - (44%)
• Gaps: 131/489 - (26%)

  Fly    19 GQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIRP 83
            |.|.:|||||.|:||||||..:|::||::|..|||||.||||||||||||||||.|:.|||||||
Mouse     9 GHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRP 73

  Fly    84 GVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSISRLLR----- 143
            ||||||||:||||.:..:|.:.|:..|.:|:||||.:|:..||||....||||||:|::|
Mouse    74 GVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQ 138

  Fly   144 ---------------------------------GSSGSGTSHSIDGILG----GGAGSVGSEDES 171
                                             .|...|:::||:|:||    |.......:|..
Mouse   139 PFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGNDNKRKMDDSD 203

  Fly   172 ED------DAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQ 230
            :|      |::.|....||..|: .|||...::|||..|.|..||:.|...
Mouse   204 QDSCRLSIDSQSSSSGPRKHLRT-DTFSQHHLEALECPFERQHYPEAYASP-------------- 253

  Fly   231 VWFSNRRARLRKQLNTQQVPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSWPSSGAYENHAAY 295
                   :..:.:.....:|..........||.|:|..|   :|.:|.:.|::|.  ..:.|:.:
Mouse   254 -------SHTKGEQGLYPLPLLNSALDDGKATLTSSNTP---LGRNLSTHQTYPV--VADPHSPF 306

  Fly   296 GGSVASMSP-ASSTSGTSSAAHSPVQTQAQQPGTGS------------EFMTSTYG--------- 338
              ::...:| .||:|.|.|:..|......||.|:|.            ....|.||
Mouse   307 --AIKQETPELSSSSSTPSSLSSSAFLDLQQVGSGGPAGASVPPFNAFPHAASVYGQFTGQALLS 369

  Fly   339 ----VGSSNATYPSAAYSMPQTPATSAEQLRSQFASAAASG------------SHHPSTWDSYNF 387
                ||.:...||      |..|.:.    :..:||:|.:|            ||.|  :.||:.
Mouse   370 GREMVGPTLPGYP------PHIPTSG----QGSYASSAIAGMVAGSEYSGNAYSHTP--YSSYSE 422

  Fly   388 AGSFFPPASAAGNHISGYHHQVDQKSSMMTTAPT 421
            |.. ||.:|...   |.|::....:.|...|:.|
Mouse   423 AWR-FPNSSLLS---SPYYYSSTSRPSAPPTSAT 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	79/123 (64%)
		homeodomain	186..243	CDD:238039	12/56 (21%)
Pax8	NP_035170.1	PAX	9..133	CDD:128645	79/123 (64%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	12..68		38/55 (69%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	87..135		21/47 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..224		14/64 (22%)
		Pax2_C	344..455	CDD:372091	27/125 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810