Protein Alignment gsb and Pax6

DIOPT Version :9

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_001231127.1
• Gene: Pax6 / 18508
• MGIID: 97490
• Length: 436
• Species: Mus musculus
• Alignment Length: 464
• Identity: 172/464 - (37%)
• Similarity: 231/464 - (49%)
• Gaps: 131/464 - (28%)

  Fly    23 VNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLR--------------VSHGCVSKILN 73
            ||||||||:||||||:..|::|||:|.:|.|||.|||.|:              ||:|||||||.
Mouse     8 VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENVSNGCVSKILG 72

  Fly    74 RFQETGSIRPGVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSI 138
            |:.|||||||..|||||||||||::.|:|.:.|:..|.||:||||.:|:..|||...|.||||||
Mouse    73 RYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSI 137

  Fly   139 SRLLR----------------------GSSGS---------GTS----HSIDGIL---GGG--AG 163
            :|:||                      |.:||         |||    .:.||..   |||  ..
Mouse   138 NRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGGGENTN 202

  Fly   164 SVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEAR 228
            |:.|..|..|:|:..:|||||.:|:||:|:.:||:|||:.|.||.||||:.||.||....|.|||
Mouse   203 SISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEAR 267

  Fly   229 VQVWFSNRRARLRKQ--LNTQQ-----VPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSWPSS 286
            :|||||||||:.|::  |..|:     .||..|.|:|| :|......|.|...:|.::|
Mouse   268 IQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSF-STSVYQPIPQPTTPVSSFTS------ 325

  Fly   287 GAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQA----QQPGTGSEFMTSTYGVGSSNATYP 347
                      ||:...:..:.|:..|:....|..|.|    .||...|:  ||:|
Mouse   326 ----------GSMLGRTDTALTNTYSALPPMPSFTMANNLPMQPPVPSQ--TSSY---------- 368

  Fly   348 SAAYSMPQTPATSAEQLRSQFASAAASGSHHPSTWDSYNFAGSFFPPASAAGNHISGYHHQVDQK 412
              :..:|.:|:.:..                  ::|:|.      ||           |.|....
Mouse   369 --SCMLPTSPSVNGR------------------SYDTYT------PP-----------HMQTHMN 396

  Fly   413 SSMMTTAPT 421
            |..|.|:.|
Mouse   397 SQPMGTSGT 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	77/133 (58%)
		homeodomain	186..243	CDD:238039	34/56 (61%)
Pax6	NP_001231127.1	PAX	4..142	CDD:128645	77/133 (58%)
		Homeobox	228..281	CDD:395001	32/52 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810