DRSC/TRiP Functional Genomics Resources

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Protein Alignment gsb and Pax4

DIOPT Version :9

Sequence 1:NP_523863.1 Gene:gsb / 38005 FlyBaseID:FBgn0001148 Length:427 Species:Drosophila melanogaster
Sequence 2:NP_035168.1 Gene:Pax4 / 18506 MGIID:97488 Length:349 Species:Mus musculus


Alignment Length:340 Identity:132/340 - (38%)
Similarity:171/340 - (50%) Gaps:69/340 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 GQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIRP 83
            |...||||||:|:||||||...|:|||::|..|:|||.|||.|:||:|||||||.|:..||.:.|
Mouse     5 GLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEP 69

  Fly    84 GVIGGSKPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSISRLLRGSSGS 148
            ..|||||||:|||.:.:||.:||...|.:|:|||:.:|...|:|.:..|||||||:|:||.....
Mouse    70 KCIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQHQLCTEGLCTQDKAPSVSSINRVLRALQED 134

  Fly   149 GTSH----SIDGILGGGAGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQY 209
            .:.|    ....:|.....|..|...:.....|..     ..|:||.||..|.:|||:.|.|.||
Mouse   135 QSLHWTQLRSPAVLAPVLPSPHSNCGAPRGPHPGT-----SHRNRTIFSPGQAEALEKEFQRGQY 194

  Fly   210 PDVYTREELAQSTGLTEARVQVWFSNRRARLRKQ-------------------------LNTQQ- 248
            ||...|.:||.:|.|.|..|:||||||||:.|:|                         ::.|| 
Mouse   195 PDSVARGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWEAQLPGASQDLTVPKNSPGIISAQQS 259

  Fly   249 ---VPSFA-----PTSTSF-----GATP------TTSAA------------PAPNMGMSLYSSQS 282
               |||.|     |.|.||     |..|      |:|.|            |   :..|.|...:
Mouse   260 PGSVPSAALPVLEPLSPSFCQLCCGTAPGRCSSDTSSQAYLQPYWDCQSLLP---VASSSYVEFA 321

  Fly   283 WPSSGAYENHAAYGG 297
            ||....:..|...||
Mouse   322 WPCLTTHPVHHLIGG 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gsbNP_523863.1 PAX 19..143 CDD:128645 70/123 (57%)
homeodomain 186..243 CDD:238039 31/56 (55%)
Pax4NP_035168.1 PAX 5..129 CDD:128645 70/123 (57%)
PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 8..64 36/55 (65%)
RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 83..131 22/47 (47%)
Homeobox 174..226 CDD:278475 29/51 (57%)
Transcription repression 278..349 14/62 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0849
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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