Protein Alignment gsb and pax-3

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_496189.2
• Gene: pax-3 / 185022
• WormBaseID: WBGene00003939
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 315
• Identity: 130/315 - (41%)
• Similarity: 175/315 - (55%)
• Gaps: 37/315 - (11%)

  Fly    19 GQGRVNQLGGVFINGRPLPNHIRRQIVEMAAAGVRPCVISRQLRVSHGCVSKILNRFQETGSIRP 83
            |||||||||||||||||||.|:|..|:.||..|::||.|||||:||||.|||||||:.|||||.|
 Worm    13 GQGRVNQLGGVFINGRPLPIHVRHAIISMAKKGIKPCHISRQLKVSHGAVSKILNRYAETGSISP 77

  Fly    84 GVIGGS-KPRVATPDIESRIEELKQSQPGIFSWEIRAKLIEAGVCDKQNAPSVSSISRLLRGSSG 147
            |.|||| :.|:....:|..|.......|.:.:.|:|..||...:|.|.|||:|.:|.||: |:.|
 Worm    78 GQIGGSPRARLTVQAVEKEILIACDENPQMSAAELRDWLIHKDICTKGNAPTVPAIKRLI-GNKG 141

  Fly   148 SGT---------SHSIDGILGGGAGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERI 203
            .|.         |:|||.|||...... |:..|:|:...|.......||:||:|:.:|:|.||..
 Worm   142 VGVPKKMERKRLSYSIDSILGISIDEC-SKSSSDDEEGSSPSNDASSRRNRTSFTAEQLDVLENA 205

  Fly   204 FARTQYPDVYTREELAQSTGLTEARVQVWFSNRRARLRK------QLNTQQVPSFAPTSTSFGAT 262
            |....||....||.:::.|||:|.::..||||||||.||      |.|.|          .||::
 Worm   206 FRADTYPHANARESISKETGLSEEKIMTWFSNRRARCRKNMPMYQQYNVQ----------GFGSS 260

  Fly   263 PTT--SAAPAPNMGMSLYSSQSWPSSGAYENHAAYGGSVASMSPASSTSGTSSAA 315
            |.:  :..|:|.|.:..||:..       :.:..:...:...||.||.|...|::
 Worm   261 PPSYPTLLPSPMMFLPSYSTSP-------QLNPLFFQHILQSSPPSSQSSPPSSS 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645	71/124 (57%)
		Homeodomain	186..242	CDD:459649	26/55 (47%)
pax-3	NP_496189.2	PAX	13..141	CDD:238076	72/128 (56%)
		Homeodomain	188..244	CDD:459649	26/55 (47%)