Protein Alignment gsb and Otx1

DIOPT Version :10

• Sequence 1: NP_523863.1
• Gene: gsb / 38005
• FlyBaseID: FBgn0001148
• Length: 427
• Species: Drosophila melanogaster
• Sequence 2: NP_035153.1
• Gene: Otx1 / 18423
• MGIID: 97450
• Length: 355
• Species: Mus musculus
• Alignment Length: 284
• Identity: 93/284 - (32%)
• Similarity: 132/284 - (46%)
• Gaps: 47/284 - (16%)

  Fly   161 GAGSVGSEDESEDDAEPSV---QLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQST 222
            |...:|....:.|...|||   ...|||||.||||:..|:|.||.:||:|:|||::.|||:|...
Mouse    11 GMNGLGLAGPAMDLLHPSVGYPATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKI 75

  Fly   223 GLTEARVQVWFSNRRARLRKQ------LNTQQV-PSFAPTSTSFGATPTTSAAPAPNMGMSLYSS 280
            .|.|:||||||.||||:.|:|      ..|:.| ...:|...|.|:..:....| |.:..|..||
Mouse    76 NLPESRVQVWFKNRRAKCRQQQQSGNGTKTRPVKKKSSPVRESSGSESSGQFTP-PAVSSSASSS 139

  Fly   281 QSWPSSGAYENHAAYGGSVASMSPASSTSGTSSAAHSPVQTQAQ-QPGTGSEFMTSTYGVGSSNA 344
            .|  :|.|..|.||...:....:|.::.|..|:...|.:.:.|. .||:...         |.:.
Mouse   140 SS--ASSASANPAAAAAAGLGGNPVAAASSLSTPTASSIWSPASISPGSAPT---------SVSV 193

  Fly   345 TYPSAAYSMPQTPATSAEQLRSQFASAAASGSHHPSTWDSYNFAGSF---FPPASAA---GNHIS 403
            ..|.||      |:.::...||..|.||.:.:.:|.   ||...||:   :|..|::   |...|
Mouse   194 PEPLAA------PSNASCMQRSVAAGAATAAASYPM---SYGQGGSYGQGYPAPSSSYFGGVDCS 249

  Fly   404 GY------HHQVDQKSSMMTTAPT 421
            .|      ||...|.|.|   ||:
Mouse   250 SYLAPMHSHHHPHQLSPM---APS 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645
		Homeodomain	186..242	CDD:459649	32/55 (58%)
Otx1	NP_035153.1	Homeodomain	39..95	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..144		14/55 (25%)
		TF_Otx	178..274	CDD:427350	30/114 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	257..306		7/17 (41%)