DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gsb and Cphx1

DIOPT Version :9

Sequence 1:	NP_523863.1	Gene:	gsb / 38005	FlyBaseID:	FBgn0001148	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_780551.1	Gene:	Cphx1 / 105594	MGIID:	2145733	Length:	182	Species:	Mus musculus

Alignment Length:	188	Identity:	42/188 - (22%)
Similarity:	76/188 - (40%)	Gaps:	29/188 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 GSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLTEARVQ 230
            |:.:..::.::...:...:..:.|..||.|::..|::.||...|||..|::|||:......:.:.
Mouse     8 GAPETKDNRSKARKRYGSRNSKPRHKFSRDELKRLKQEFAYAPYPDFTTKDELARQFQCEVSVID 72

  Fly   231 VWFSNRRARLRKQLNT--------QQVPSFAPTSTSFGATPTTSAAPAPNMGMSLYSSQSWPSSG 287
            .||.|:||||..:|.:        ::...:..|.......|..|.....:.. |:..|....|.|
Mouse    73 NWFQNKRARLAPELKSKISAMRRMRRCQDYMRTGHQDTQPPKASGEQYSSCD-SVVRSIGRQSIG 136

  Fly   288 AYENHAAYGGSVASMSPASSTSGTSSAAHSPV--------QTQAQQPGTGSEFMTSTY 337
            ..| |....|..:|..|.:.|       ..||        |.:.|:    :::.|.:|
Mouse   137 TVE-HQGAAGRESSFRPTNFT-------FPPVYEQYYMGDQLETQE----TQYFTFSY 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645
gsb	NP_523863.1	homeodomain	186..243	CDD:238039	21/56 (38%)
Cphx1	NP_780551.1	homeodomain	29..82	CDD:238039	19/52 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810