DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gsb and mxtx1

DIOPT Version :9

Sequence 1:	NP_523863.1	Gene:	gsb / 38005	FlyBaseID:	FBgn0001148	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_571635.2	Gene:	mxtx1 / 100149566	ZFINID:	ZDB-GENE-000710-7	Length:	309	Species:	Danio rerio

Alignment Length:	258	Identity:	67/258 - (25%)
Similarity:	95/258 - (36%)	Gaps:	96/258 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 GAGSVGSEDESEDDAEPSVQLKRKQRRSRTTFSNDQIDALERIFARTQYPDVYTREELAQSTGLT 225
            |:|:|.               :...||.||:||.:.::.|...|....||.:..||.|:|:|||.
Zfish    15 GSGAVS---------------RSASRRKRTSFSKEHVELLRATFETDPYPGISLRESLSQTTGLP 64

  Fly   226 EARVQVWFSNRRARL------RKQLNTQQVPSFAPTST-----------SFGATPTTSAAP---- 269
            |:|:||||.|||||.      :|.|....:|::....|           |.|||.|..:.|
Zfish    65 ESRIQVWFQNRRARTLKCKGGKKPLWQTDLPAYNNMQTSPMQIHRKNNESSGATGTLCSPPPAYP 129

  Fly   270 ----------------APNMGMSL-----YSSQSWPSSGAYENHAAYGGSVASMSPASSTS---- 309
                            .|: .||:     |.:.|:..|.|.::|         |||:...|
Zfish   130 DRIKEEMEKDAVCGCDTPS-SMSISDDSGYCTPSYHQSRAIQSH---------MSPSPLLSPEHQ 184

  Fly   310 -----GTSSAAHSPVQTQAQQPGTGSEFMTSTYGVGSSNATYPSAAYS--------MPQTPAT 359
                 |......||:.:           |.|.|.: .:.|..|...||        .|.||.|
Zfish   185 MPPNWGVRYGRRSPMSS-----------MWSPYHL-EAYACNPGFFYSHSEKHNTLQPLTPVT 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gsb	NP_523863.1	PAX	19..143	CDD:128645
gsb	NP_523863.1	homeodomain	186..243	CDD:238039	28/62 (45%)
mxtx1	NP_571635.2	HOX	24..78	CDD:197696	26/53 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810