DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gsb-n and Pax4

DIOPT Version :9

Sequence 1:	NP_523862.1	Gene:	gsb-n / 38004	FlyBaseID:	FBgn0001147	Length:	449	Species:	Drosophila melanogaster
Sequence 2:	NP_113987.1	Gene:	Pax4 / 83630	RGDID:	620433	Length:	349	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	111/250 - (44%)
Similarity:	148/250 - (59%)	Gaps:	20/250 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKILNRYQETGSIRP 84
            |...||||||:|:||||||...|.:||::|..|:|||.|||.|:||:|||||||.||..||.:.|
  Rat     5 GLSSVNQLGGLFVNGRPLPLDTRQQIVQLAIRGMRPCDISRSLKVSNGCVSKILGRYYRTGVLEP 69

  Fly    85 GVIGGSKPKVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFA---DPPSTSSISRLLRGSDRG 146
            ..||||||::.:|.:..||.:|:.|.|::|:|||:.:|..||..   ..||.|||:|:||..
  Rat    70 KGIGGSKPRLATPAVVARIAQLKDEYPALFAWEIQRQLCAEGLCTQDKAPSVSSINRVLRAL--- 131

  Fly   147 SEDGRKDYT---INGILG-GRDSDISDTESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYP 207
            .||.|..:|   ...:|. ...|..|:.|:..| |......|:||.|:..|.||||:.|.|.|||
  Rat   132 QEDQRLHWTQLRSPAVLAPALPSPHSNCEAPRG-PHPGTSHRNRTIFSPGQAEALEKEFQRGQYP 195

  Fly   208 DVYTREELAQTTALTEARIQVWFSNRRARLRKHS---------GGSNSGLSPMNS 253
            |...|.:||..|:|.|..::||||||||:.|:..         |.|...:.|.:|
  Rat   196 DSVVRGKLAAATSLPEDTVRVWFSNRRAKWRRQEKLKWETQMPGASQDLMVPKDS 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	PAX	20..141	CDD:278709	65/123 (53%)
gsb-n	NP_523862.1	Homeobox	185..238	CDD:278475	28/52 (54%)
Pax4	NP_113987.1	PAX	5..129	CDD:128645	65/123 (53%)
		PAI subdomain. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00381	8..64		36/55 (65%)
		RED subdomain. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00381	83..131		20/47 (43%)
		Homeobox	174..226	CDD:278475	28/51 (55%)
		Transcription repression	278..349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810