Protein Alignment gsb-n and Pax8

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_112403.2
• Gene: Pax8 / 81819
• RGDID: 620434
• Length: 457
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 153/508 - (30%)
• Similarity: 214/508 - (42%)
• Gaps: 153/508 - (30%)

  Fly     7 NSLRPLFAGYPFQGQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSK 71
            ||:|        .|.|.:|||||.|:||||||..:|.:||::|..|||||.||||||||||||||
  Rat     4 NSIR--------SGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK 60

  Fly    72 ILNRYQETGSIRPGVIGGSKPKVTSPEIETRIDELRKENPSIFSWEIREKLIKEGFAD---PPST 133
            ||.||.|||||||||||||||||.:|::..:|.:.:::||::|:||||::|:.||..|   .||.
  Rat    61 ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSV 125

  Fly   134 SSISRLLR-----------------------------GSDRGSEDGRKD-----YTINGILG--- 161
            |||:|::|                             .:....|..:.|     |:|||:||
  Rat   126 SSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQ 190

  Fly   162 -GRDS----DISD-------TESEPGIPLKRKQRRSRTTFTAEQLEALERAFSRTQYPDVYTREE 214
             |.|:    |.||       .:|:......||..|: .||....||.||..|.|..||:.|...
  Rat   191 PGSDNKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRT-DTFGQHHLEPLECPFERQHYPEAYASP- 253

  Fly   215 LAQTTALTEARIQVWFSNRRARLRKHSGGSNSGLSPMNSGSSNVGVG-VGLSGATAPLGYG---- 274
                                    .|:.| ..||.|:...:|.:..| ..|:.:..|||..
  Rat   254 ------------------------SHTKG-EQGLYPLPLLNSTLDDGKATLTPSNTPLGRNLSTH 293

  Fly   275 ---PLGVGSMAGYSPAPGTTATGAGMNDGVHHAAHAPSSHHSAATAAAAAHHHTQMGGYDLVQSA 336
               |:.....:.|:....|....:        ::..|||..|:|.             .||.|..
  Rat   294 QTYPVVADPHSPYAIKQETPELSS--------SSSTPSSLSSSAF-------------LDLQQVG 337

  Fly   337 AQHGFPGGFAQPGHFGSQNYYHQDYSKLTIDDFSKLTADSVSKISPSLHLSDNYSKLEAPSNWSQ 401
            :  |.|.|.:.| .|.:.::....|.:.|    .:........:.|:|
  Rat   338 S--GGPAGASVP-PFNAFSHAASVYGQFT----GQALLSGREMVGPTL----------------- 378

  Fly   402 AAYHAAANYNAHVAQHQLNDYAAAAAHGNPA------SAYSHPLPTQGQAKYW 448
                  ..|..|:.......||::|..|..|      :|||| .|....::.|
  Rat   379 ------PGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYSH-TPYASYSEAW 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	77/123 (63%)
		Homeodomain	183..239	CDD:459649	12/55 (22%)
Pax8	NP_112403.2	PAX	9..133	CDD:128645	77/123 (63%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	12..68		39/55 (71%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	87..135		19/47 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..226		16/66 (24%)
		Pax2_C	344..456	CDD:463563	19/110 (17%)