Protein Alignment gsb-n and RHOXF2B

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_001093155.1
• Gene: RHOXF2B / 727940
• HGNCID: 33519
• Length: 288
• Species: Homo sapiens
• Alignment Length: 216
• Identity: 63/216 - (29%)
• Similarity: 95/216 - (43%)
• Gaps: 48/216 - (22%)

  Fly    96 SPEIETRIDELRKENPSIFSW--EIREKLIKEGFADP---PSTSSISRLLRGSDRGSE--DG--- 150
            ||.::.. .||:..|..:.|.  |::|   :|..|.|   ..|::..:|.....:|.|  ||
Human    16 SPAVDDE-KELQDMNAMVLSLTEEVKE---EEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGE 76

  Fly   151 RKDYTINGILG-----------GRDSDISD---TESEPGIPLKR------------KQRRSRTTF 189
            .||....|:.|           |.|.::.|   :|.|||....|            .|:.:...|
Human    77 EKDGGGAGVPGHLWEGNLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAF 141

  Fly   190 TAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHSGGSNS-GLSPMNS 253
            |..||:.||..|.|.|:|..:.|..||::..:||..:|:||.||||:.|:|.....: .:.|..:
Human   142 TPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMA 206

  Fly   254 GSSNVGVGVGLSGA---TAPL 271
                ||..|.::.|   ||||
Human   207 ----VGQPVMVTAAEAITAPL 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	13/49 (27%)
		Homeodomain	183..239	CDD:459649	22/55 (40%)
RHOXF2B	NP_001093155.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..136		30/123 (24%)
		Homeodomain	139..191	CDD:459649	22/51 (43%)
		PRK02287	<183..>232	CDD:235024	15/45 (33%)
		Nuclear localization signal. /evidence=ECO:0000250	186..195		4/8 (50%)