Protein Alignment gsb-n and PAX7

DIOPT Version :10

• Sequence 1: NP_523862.1
• Gene: gsb-n / 38004
• FlyBaseID: FBgn0001147
• Length: 449
• Species: Drosophila melanogaster
• Sequence 2: NP_002575.1
• Gene: PAX7 / 5081
• HGNCID: 8621
• Length: 520
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 210/452 - (46%)
• Similarity: 259/452 - (57%)
• Gaps: 87/452 - (19%)

  Fly    15 GYPFQ-----GQGRVNQLGGVFINGRPLPNHIRLKIVEMAASGVRPCVISRQLRVSHGCVSKILN 74
            |:|.:     |||||||||||||||||||||||.||||||..|:||||||||||||||||||||.
Human    24 GFPLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILC 88

  Fly    75 RYQETGSIRPGVIGGSKPK-VTSPEIETRIDELRKENPSIFSWEIREKLIKEGFAD---PPS--T 133
            |||||||||||.||||||: |.:|::|.:|:|.::|||.:||||||::|:|:|..|   .||  .
Human    89 RYQETGSIRPGAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLV 153

  Fly   134 SSISRLLR----------GSDRGSEDGRK--DYTINGILGGRDSDI---SDTESEPGIPLKRKQR 183
            |||||:||          .:|:..:||.|  .::|:||||.:.:.:   ||.||||.:|||||||
Human   154 SSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQR 218

  Fly   184 RSRTTFTAEQLEALERAFSRTQYPDVYTREELAQTTALTEARIQVWFSNRRARLRKHSGGSNSGL 248
            ||||||||||||.||:||.||.|||:||||||||.|.|||||:||||||||||.||.:|.:.  |
Human   219 RSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQ--L 281

  Fly   249 SPMNSGSSNVGVGVGLSGATAPLGYGPLGVGSMAGYSPAPGTTATGAGMNDG---VHHAAH-APS 309
            :..|.              ..|.|:.|.|:.::..|.....|..|.....||   ||.... .||
Human   282 AAFNH--------------LLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPS 332

  Fly   310 SHHSAATAAAAAHHHTQMGGYDLVQSAAQHGFPGGFAQPGHFGSQNYYHQDYSKLTIDDFSKLTA 374
            :.|....|||||...|. ..|     .|:|.|                 ..||    |.|
Human   333 TMHQGGLAAAAAAADTS-SAY-----GARHSF-----------------SSYS----DSF----- 365

  Fly   375 DSVSKISPSLHLSDNYSKLEAPSNWSQAAYHAAANYNAHVAQHQLNDYAAAAAHGNPASAYS 436
              ::..:||.|::      ...:..|........|.:|...|.|. |::.:..||...||.|
Human   366 --MNPAAPSNHMN------PVSNGLSPQVMSILGNPSAVPPQPQA-DFSISPLHGGLDSATS 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gsb-n	NP_523862.1	HTH_CRP	20..141	CDD:481199	92/126 (73%)
		Homeodomain	183..239	CDD:459649	46/55 (84%)
PAX7	NP_002575.1	paired box domain	34..164		94/129 (73%)
		PAX	34..163	CDD:238076	94/128 (73%)
		octapeptide	86..93		5/6 (83%)
		paired homeodomain	217..275		48/57 (84%)
		Homeodomain	218..274	CDD:459649	46/55 (84%)
		Pax7	347..385	CDD:403540	13/77 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..409		5/20 (25%)